Global initiative for the diagnosis, management, and prevention of chronic obstructive lung disease. The 2020 GOLD science committee report on COVID-19 and …

DMG Halpin, GJ Criner, A Papi, D Singh… - American journal of …, 2021 - atsjournals.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has raised
many questions about the management of patients with chronic obstructive pulmonary …

Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19

JP Bridges, EK Vladar, H Huang, RJ Mason - Thorax, 2022 - thorax.bmj.com
COVID-19 has different clinical stages, and effective therapy depends on the location and
extent of the infection. The purpose of this review is to provide a background for …

[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)

A Aleem, AS Ab, AK Slenker - 2021 - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …

Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

F D'Agnillo, KA Walters, Y Xiao, ZM Sheng… - Science translational …, 2021 - science.org
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is characterized by respiratory distress, multiorgan …

Extracorporeal membrane oxygenation for COVID-19: updated 2021 guidelines from the extracorporeal life support organization

J Badulak, MV Antonini, CM Stead… - Asaio …, 2021 - journals.lww.com
Disclaimer: This is an updated guideline from the Extracorporeal Life Support Organization
(ELSO) for the role of extracorporeal membrane oxygenation (ECMO) for patients with …

[HTML][HTML] Features, evaluation, and treatment of coronavirus (COVID-19)

M Cascella - 2020 - ncbi.nlm.nih.gov
Objectives: Screen individuals based on exposure and symptom criteria to identify potential
COVID-19 cases. Identify the clinical features and radiological findings expected in patients …

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

DJ Downes, AR Cross, P Hua, N Roberts… - Nature …, 2021 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) disease (COVID-19)
pandemic has caused millions of deaths worldwide. Genome-wide association studies …

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

CGK Ziegler, VN Miao, AH Owings, AW Navia, Y Tang… - Cell, 2021 - cell.com
SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals
present with isolated upper respiratory symptoms, suggesting potential to constrain viral …

[HTML][HTML] Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

R Bussani, E Schneider, L Zentilin, C Collesi, H Ali… - …, 2020 - thelancet.com
Background COVID-19 is a deadly pulmonary disease with peculiar characteristics, which
include variable clinical course and thrombophilia. A thorough understanding of the …

Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience

C Bryce, Z Grimes, E Pujadas, S Ahuja, MB Beasley… - Modern …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical
syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe …