Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …

Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …

Severe or life threatening infections are common among patients in the intensive care unit
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …

Purpose Individualising drug dosing using model-informed precision dosing (MIPD) of beta-
lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing …

Antibiotic resistance is recognised as a global threat to human health by national healthcare
agencies, governments and medical societies, as well as the World Health Organization …

Antibiotics are recognized widely for their benefits when used appropriately. However, they
are often used inappropriately despite the importance of responsible use within good clinical …

Ventilator-associated pneumonia (VAP) is a serious intensive care unit (ICU)-related
infection in mechanically ventilated patients that is frequent, as more than half of antibiotics …

Severe infections caused by DTR-GNB pose a formidable challenge for healthcare
providers and represent a growing global health issue. The proper administration and …

Rising antibiotic resistance amidst indiscriminate antibiotic use is a growing public health
concern. Efforts to curb this trend have had limited success, particularly in developing …

Antimicrobial resistance is a global threat to human health and welfare, food safety, and
environmental health. The rapid detection and quantification of antimicrobial resistance are …