Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

Introduction: Calcitonin gene-related peptide (CGRP) is a key molecule in migraine
pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients …

Hemiplegic migraine is a rare form of migraine with aura that involves motor aura
(weakness). This type of migraine can occur as a sporadic or a familial disorder. Familial …

Migraine is a common condition with disabling attacks that burdens people in the prime of
their working lives. Despite years of research into migraine pathophysiology and …

Background Although the involvement of calcitonin gene-related peptide (CGRP) in
migraines is well-established, its specific role in investigating the aura phase, which often …

Background Migraine is a common debilitating condition whose main attributes are severe
recurrent headaches with accompanying sensitivity to light and sound, nausea and vomiting …

Migraine is a disease for which there is still no defined pathophysiological etiology and few
translational models. The organic nitrate nitroglycerin has been in use as an experimental …

Migraine and sleep disorders are common chronic diseases in the general population, with
significant negative social and economic impacts. The association between both of these …

Vascular theories of migraine and cluster headache have dominated for many years the
pathobiological concept of these disorders. This view is supported by observations that …