The Sonogashira reaction: a booming methodology in synthetic organic chemistry

R Chinchilla, C Nájera - Chemical reviews, 2007 - ACS Publications
The array of transition-metal-catalyzed cross-coupling reactions can easily be considered
nowadays cornerstones in the field of organic synthesis. 1, 2 Among them, the palladium …

Photochemical reactions as key steps in organic synthesis

N Hoffmann - Chemical Reviews, 2008 - ACS Publications
Since the beginning of scientific chemistry, chemists have been interested in light as an
energy source to induce chemical reactions. 1 Absorbing light, molecules reach an …

A survey of the role of noncovalent sulfur interactions in drug design

BR Beno, KS Yeung, MD Bartberger… - Journal of medicinal …, 2015 - ACS Publications
Electron deficient, bivalent sulfur atoms have two areas of positive electrostatic potential, a
consequence of the low-lying σ* orbitals of the C–S bond that are available for interaction …

Arynes and cyclohexyne in natural product synthesis

CM Gampe, EM Carreira - Angewandte Chemie International …, 2012 - Wiley Online Library
This Minireview highlights recent advances in the field of aryne and cyclohexyne chemistry
that have allowed the extraordinary reactivity of these entities to be harnessed during the …

Concerted reactions that produce diradicals and zwitterions: electronic, steric, conformational, and kinetic control of cycloaromatization processes

RK Mohamed, PW Peterson, IV Alabugin - Chemical Reviews, 2013 - ACS Publications
The broad utility of cyclic structures accounts for the key roles that cycle-forming reactions
play in synthetic designs. Most of these reactions can be classified as either a cyclization of …

Preparation of carbon nanodots from single chain polymeric nanoparticles and theoretical investigation of the photoluminescence mechanism

B Zhu, S Sun, Y Wang, S Deng, G Qian… - Journal of Materials …, 2013 - pubs.rsc.org
Even after several years of research, controlled synthesis of photoluminescent carbon
nanodots (C-dots) still constitutes a major challenge, and investigation of their …

Conjugated oligoenynes based on the diethynylethene unit

MB Nielsen, F Diederich - Chemical reviews, 2005 - ACS Publications
1, 2-Diethynylethenes (hex-3-ene-1, 5-diynes, DEEs) have found wide interest as potential
antitumor agents in medicinal chemistry1 and as redox active or chromophoric units in …

Design, synthesis, and biological activity of unnatural enediynes and related analogues equipped with pH-dependent or phototriggering devices

M Kar, A Basak - Chemical reviews, 2007 - ACS Publications
Design, Synthesis, and Biological Activity of Unnatural Enediynes and Related Analogues
Equipped with pH-Dependent or Phototriggering Devices | Chemical Reviews ACS ACS …

[HTML][HTML] Antibody Drug Conjugates for Cancer Therapy: From Metallodrugs to Nature-Inspired Payloads

G Tonon, F Rizzolio, F Visentin, T Scattolin - International Journal of …, 2024 - mdpi.com
This review highlights significant advancements in antibody–drug conjugates (ADCs)
equipped with metal-based and nature-inspired payloads, focusing on synthetic strategies …

Bottom-up wet-chemical synthesis of a two-dimensional porous carbon material with high supercapacitance using a cascade coupling/cyclization route

Y Xu, RS Sprick, NJ Brownbill, F Blanc, Q Li… - Journal of Materials …, 2021 - pubs.rsc.org
Wet-chemical bottom-up synthesis methods for two-dimensional (2D) layered materials are
less explored than the top-down exfoliation of bulk materials. Here, we set out to synthesize …