Based on spiral 3D tomography a large variety of applications have been developed during
the last decade to asses bone mineral density, bone macro and micro structure, and bone …

Authored by experts of international renown, the new edition of The Biomechanics of Back
Pain forms a bridge between the latest research and the effective clinical management of …

A vertebral fracture is a marker of bone fragility and is associated with a downward spiral of
recurrent fractures known as the vertebral fracture cascade. Etiology of this unfortunate …

Abstract The International Society for Clinical Densitometry (ISCD) has developed new
official positions for the clinical use of quantitative computed tomography (QCT)-based finite …

The mechanism of vertebral wedge fractures remains unclear and may relate to typical
variations in the mechanical behavior of the intervertebral disc. To gain insight, we tested 16 …

Vertebral strength, a key etiologic factor of osteoporotic fracture, may be affected by the
relative amount of vertically oriented trabeculae. To better understand this issue, we …

This article presents an effort toward building an artificial intelligence (AI) assisted
framework, coined ReconGAN, for creating a realistic digital twin of the human vertebra and …

The biomechanical mechanisms leading to vertebral fractures are not well understood.
Clinical and laboratory evidence suggests that the vertebral endplate plays a key role in …

Excessive mechanical loading of the spine is a critical factor in vertebral fracture initiation.
Most vertebral fractures develop spontaneously or due to mild trauma, as physiological …

To provide mechanistic insight into the etiology of osteoporotic wedge fractures, we
investigated the spatial distribution of tissue at the highest risk of initial failure within the …