The intellectual base and research fronts of IL-37: A bibliometric review of the literature from WoSCC

Y Qin, S Ren, B Shao, H Qin, H Wang, G Li… - Frontiers in …, 2022 - frontiersin.org
Background IL-37 is a recently identified cytokine with potent immunosuppressive functions.
The research fronts of IL-37 are worth investigating, and there is no bibliometric analysis in …

Clinical implications of IL-32, IL-34 and IL-37 in atherosclerosis: speculative role in cardiovascular manifestations of COVID-19

CC Law, R Puranik, J Fan, J Fei… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis, which is a primary cause of cardiovascular disease (CVD) deaths around
the world, is a chronic inflammatory disease that is characterised by the accumulation of lipid …

IL‑37 suppresses macrophage ferroptosis to attenuate diabetic atherosclerosis via the NRF2 pathway

J Xu, X Han, N Xia, Q Zhao… - Experimental and …, 2023 - spandidos-publications.com
IL‑37 is a newly discovered inflammatory factor. However, the protective effect and
underlying mechanisms of IL‑37 on atherosclerosis remain unclear. In the present study, IL …

T cells in cardiac health and disease

P Martín, F Sánchez-Madrid - The Journal of Clinical Investigation, 2025 - jci.org
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality
worldwide, with inflammation playing a pivotal role in its pathogenesis. T lymphocytes are …

[HTML][HTML] Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis

N Ma, C Yuan, J Shi, Q Zhu, Y Liu, X Ma, B Li, W Gong… - JCI insight, 2022 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a local and/or systemic inflammatory disease that starts with acinar
cell injury and necrosis; it has no effective medical treatment and thus remains a life …

Comparison of cell-based and nanoparticle-based therapeutics in treating atherosclerosis

WX Goh, YY Kok, CY Wong - Current Pharmaceutical Design, 2023 - benthamdirect.com
Today, cardiovascular diseases are among the biggest public health threats worldwide.
Atherosclerosis, a chronic inflammatory disease with complex aetiology and pathogenesis …

IL-37—A putative therapeutic agent in cardiovascular diseases

S McCurdy, J Yap, J Irei, J Lozano… - QJM: An International …, 2022 - academic.oup.com
Although it is a member of the Interleukin (IL)-1 family, IL-37 is unique in that it has wide-
ranging anti-inflammatory characteristics. It was originally thought to prevent IL-18-mediated …

Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs

VE Brunt, AP Ikoba, BP Ziemba, DB Ballak, A Hoischen… - Geroscience, 2023 - Springer
Aging is characterized by declines in physiological function that increase risk of age-
associated diseases and limit healthspan, mediated in part by chronic low-grade …

[HTML][HTML] The Protective Role of Interleukin-37 in Cardiovascular Diseases through Ferroptosis Modulation

A Cruz-Gregorio, LM Amezcua-Guerra… - International Journal of …, 2024 - mdpi.com
The role of ferroptosis and iron metabolism dysregulation in the pathophysiology of
cardiovascular diseases is increasingly recognized. Conditions such as hypertension …

Overview of multifunctional Tregs in cardiovascular disease: From insights into cellular functions to clinical implications

V Kumar, M Narisawa, XW Cheng - The FASEB Journal, 2024 - Wiley Online Library
Regulatory T cells (Tregs) are crucial in regulating T‐cell‐mediated immune responses.
Numerous studies have shown that dysfunction or decreased numbers of Tregs may be …