Background Early recognition of xeroderma pigmentosum is important to minimize the
complications arising from the harmful effects of exposure to ultraviolet radiation. This …

The skin barrier and its endogenous protective mechanisms cope daily with exogenous
stressors, of which ultraviolet radiation (UVR) poses an imminent danger. Although the skin …

Genodermatoses are rare inherited skin diseases that frequently affect other organs. They
often have marked effects on wellbeing and may cause early death. Progress in molecular …

Melanoma in pediatric patients often presents differently from conventional adult melanoma,
including Spitz melanoma and melanoma associated with congenital melanocytic nevi …

Background Xeroderma pigmentosum (XP) is caused by impaired DNA repair of UV-
induced dipyrimidine-photoproducts. XP cells also show impaired repair/removal of ROS or …

The DUSP3 phosphatase regulates cell cycle, proliferation, apoptosis and senescence of
different cell types, lately shown as a mediator of DNA repair processes. This work evaluated …

Background Xeroderma pigmentosum (XP) is a rare autosomal‐recessive genodermatosis
resulting from a DNA‐repair defect syndrome. The purpose was to evaluate the prevention …

Xeroderma pigmentosum (XP) is an autosomal recessive genetic disease caused by a
defect in the DNA repair system, exhibiting skin cancer on sun exposure. As it is an …

The genodermatoses are a group of hereditary syndromes with skin manifestations. Many of
these conditions are associated with increased risk for specific cancers. Cutaneous …

Background Xeroderma pigmentosum (XP) is a very rare and severe genetic disorder with a
DNA repair defect of ultraviolet (UV)-induced damage. Photodynamic therapy (PDT) has …