Optimized photoclick (bio) resins for fast volumetric bioprinting

R Rizzo, D Ruetsche, H Liu… - Advanced …, 2021 - Wiley Online Library
Volumetric printing (VP) is a light‐mediated technique enabling printing of complex, low‐
defect 3D objects within seconds, overcoming major drawbacks of layer‐by‐layer additive …

Spatial‐Selective Volumetric 4D Printing and Single‐Photon Grafting of Biomolecules within Centimeter‐Scale Hydrogels via Tomographic Manufacturing

M Falandt, PN Bernal, O Dudaryeva… - Advanced materials …, 2023 - Wiley Online Library
Conventional additive manufacturing and biofabrication techniques are unable to edit the
chemicophysical properties of the printed object postprinting. Herein, a new approach is …

[HTML][HTML] Two faces of TEMPO (2, 2, 6, 6-tetramethylpiperidinyl-1-oxyl)–An antioxidant or a toxin?

M Mołoń, D Szlachcikowska, K Stępień, P Kielar… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Abstract 2, 2, 6, 6-Tetramethylpiperidine-1-oxyl, commonly known as TEMPO, is one of the
compounds called nitroxides that are used in the chemical industry for synthesis of many …

Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip …

JE Seo, V Tryndyak, Q Wu, K Dreval, I Pogribny… - Archives of …, 2019 - Springer
In vitro genotoxicity testing that employs metabolically active human cells may be better
suited for evaluating human in vivo genotoxicity than current bacterial or non-metabolically …

Performance of HepaRG and HepG2 cells in the high-throughput micronucleus assay for in vitro genotoxicity assessment

X Guo, JE Seo, D Petibone, V Tryndyak… - Journal of Toxicology …, 2020 - Taylor & Francis
The micronucleus (MN) assay is a core test used to evaluate genotoxic potential of
xenobiotics. The traditional in vitro MN assay is usually conducted in cells lacking metabolic …

Reversible Deactivation Radical Polymerization Mediated by Nitroxides and Green Chemistry

MY Zaremski, NS Melik-Nubarov - Polymer Science, Series C, 2021 - Springer
This review is the first attempt to consider application of some principles of green chemistry
to reversible-deactivation radical polymerization mediated by nitroxides. The results of …

Benchmark Dose Modeling of In Vitro Genotoxicity Data: a Reanalysis

X Guo, N Mei - Toxicological Research, 2018 - Springer
The methods of applied genetic toxicology are changing from qualitative hazard
identification to quantitative risk assessment. Recently, quantitative analysis with point of …

Effect of Low Concentration of Nitroxides on SH-SY5Y Cells Transfected with the Tau Protein

G Bartosz, N Pieńkowska, K Kut, B Cieniek… - International Journal of …, 2023 - mdpi.com
Nitroxides, stable synthetic free radicals, are promising antioxidants, showing many
beneficial effects both at the cellular level and in animal studies. However, the cells are …

Development and application of TK6-derived cells expressing human cytochrome P450s for genotoxicity testing

X Li, S Chen, X Guo, Q Wu, JE Seo, L Guo… - Toxicological …, 2020 - academic.oup.com
Metabolism plays a key role in chemical genotoxicity; however, most mammalian cells used
for in vitro genotoxicity testing lack effective metabolizing enzymes. We recently developed a …

Design of a new self-assembling antioxidant nanomedicine to ameliorate oxidative stress in zebrafish embryos

B Shashni, J Tamaoki, M Kobayashi, Y Nagasaki - Acta Biomaterialia, 2023 - Elsevier
Oxidative stress, which is a persistent state of elevated reactive oxygen species (ROS), is
implicated in the pathogeneses of several diseases, making antioxidant-based therapeutics …