We review what is currently understood about how the structure of the primary solid
component of mucus, the glycoprotein mucin, gives rise to the mechanical and biochemical …

Airway mucus is a complex viscoelastic gel that provides a defensive physical barrier and
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …

Cutaneous wound healing is complex, requiring a coordinated response by growth factors,
drugs, and resident cells of the skin. To simulate native extracellular matrix, electrospun …

Wound dressings composed of natural polymers, such as type I collagen, possess good
biocompatibility, water holding capacity, air permeability, and degradability, and can be …

Mucus covers all wet epithelia and acts as a protective barrier. In the airways of the lungs,
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …

Antibody-based therapeutics have become a major class of therapeutics with over 120
recombinant antibodies approved or under review in the EU or US. This therapeutic class …

In recent years, RNA-based therapies have gained much attention as biomedicines due to
their remarkable therapeutic effects with high specificity and potency. Lung diseases offer a …

Objectives In the context of cystic fibrosis, Pseudomonas aeruginosa biofilms often develop
in the vicinity of airway mucus, which acts as a protective physical barrier to inhaled matter …

Human respiratory mucus is a biological hydrogel that forms a protective barrier for the
underlying epithelium. Modulation of the mucus layer has been employed as a strategy to …

Background: Airway mucus provides important protective functions in health and abnormal
viscoelasticity is a hallmark of muco-obstructive lung diseases such as cystic fibrosis (CF) …