Rhodococcus equi foal pneumonia: Update on epidemiology, immunity, treatment and prevention

AI Bordin, L Huber, MG Sanz… - Equine veterinary …, 2022 - Wiley Online Library
Pneumonia in foals caused by the bacterium Rhodococcus equi has a worldwide
distribution and is a common cause of disease and death for foals. The purpose of this …

Current understanding of the equine immune response to Rhodococcus equi. An immunological review of R. equi pneumonia

TRMY Dawson, DW Horohov, WG Meijer… - Veterinary immunology …, 2010 - Elsevier
Rhodococcus equi is recognised to cause chronic purulent bronchopneumonia in foals of
less than 6 months of age. Virulent strains of the bacteria possess a large 80–90kb plasmid …

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development

R Van der Geize, AWF Grommen, GI Hessels… - PLoS …, 2011 - journals.plos.org
Rhodococcus equi causes fatal pyogranulomatous pneumonia in foals and
immunocompromised animals and humans. Despite its importance, there is currently no …

Rhodococcus equi–What is New This Decade?

MG Sanz - Veterinary Clinics: Equine Practice, 2023 - vetequine.theclinics.com
Our understanding of R equi pathogenesis has changed over the last decade, and this
knowledge has translated to a new set of recommendations regarding prophylaxis …

Oral Administration of Electron-Beam Inactivated Rhodococcus equi Failed to Protect Foals against Intrabronchial Infection with Live, Virulent R. equi

JN Rocha, ND Cohen, AI Bordin, CN Brake, S Giguère… - PloS one, 2016 - journals.plos.org
There is currently no licensed vaccine that protects foals against Rhodococcus equi–
induced pneumonia. Oral administration of live, virulent R. equi to neonatal foals has been …

Rhodococcus equi (Prescottella equi) vaccines; the future of vaccine development

C Giles, T Vanniasinkam, S Ndi… - Equine veterinary …, 2015 - Wiley Online Library
For decades researchers have been targeting prevention of R hodococcus equi
(Rhodococcus hoagui/P rescottella equi) by vaccination and the horse breeding industry …

PNAG-specific equine IgG1 mediates significantly greater opsonization and killing of Prescottella equi (formerly Rhodococcus equi) than does IgG4/7

JN Rocha, LJ Dangott, W Mwangi, RC Alaniz, AI Bordin… - Vaccine, 2019 - Elsevier
Prescottella equi (formerly Rhodococcus equi) is a facultative intracellular bacterial
pathogen that causes severe pneumonia in foals 1–6 months of age, whereas adult horses …

[HTML][HTML] Advances in understanding immunity to Rhodococcus equi infection and Vaccine Development Strategies: A Comprehensive Review

P Jhandai, K Shanmugasundaram, TK Bhattacharya… - The Microbe, 2024 - Elsevier
Rhodococcus equi is a Gram-positive, facultative intracellular bacterial pathogen which
causes persistent purulent bronchopneumonia in foals less than six months of age …

Mouse lung infection model to assess Rhodococcus equi virulence and vaccine protection

P González-Iglesias, M Scortti, I MacArthur… - Veterinary …, 2014 - Elsevier
The pathogenic actinomycete Rhodococcus equi causes severe purulent lung infections in
foals and immunocompromised people. Although relatively unsusceptible to R. equi, mice …

Proteomic analysis and immunogenicity of secreted proteins from Rhodococcus equi ATCC 33701

C Barbey, A Budin-Verneuil, S Cauchard, A Hartke… - Veterinary …, 2009 - Elsevier
Rhodococcus equi is one of the most important causes of mortality in foals between 1 and 6
months of age. Although rare, infection also occurs in a variety of other mammals including …