Cortical interneurons: fit for function and fit to function? Evidence from development and evolution
J Keijser, H Sprekeler - Frontiers in Neural Circuits, 2023 - frontiersin.org
Cortical inhibitory interneurons form a broad spectrum of subtypes. This diversity suggests a
division of labor, in which each cell type supports a distinct function. In the present era of …
division of labor, in which each cell type supports a distinct function. In the present era of …
Parametric control of flexible timing through low-dimensional neural manifolds
Biological brains possess an unparalleled ability to adapt behavioral responses to changing
stimuli and environments. How neural processes enable this capacity is a fundamental open …
stimuli and environments. How neural processes enable this capacity is a fundamental open …
Gain control of sensory input across polysynaptic circuitries in mouse visual cortex by a single G protein-coupled receptor type (5-HT2A)
R Barzan, B Bozkurt, MM Nejad, ST Süß… - Nature …, 2024 - nature.com
Response gain is a crucial means by which modulatory systems control the impact of
sensory input. In the visual cortex, the serotonergic 5-HT2A receptor is key in such …
sensory input. In the visual cortex, the serotonergic 5-HT2A receptor is key in such …
Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region
High-dimensional brain activity is often organized into lower-dimensional neural manifolds.
However, the neural manifolds of the visual cortex remain understudied. Here, we study …
However, the neural manifolds of the visual cortex remain understudied. Here, we study …
Context-invariant beliefs are supported by dynamic reconfiguration of single unit functional connectivity in prefrontal cortex of male macaques
Natural behaviors occur in closed action-perception loops and are supported by dynamic
and flexible beliefs abstracted away from our immediate sensory milieu. How this real-world …
and flexible beliefs abstracted away from our immediate sensory milieu. How this real-world …
Learning to combine top-down context and feed-forward representations under ambiguity with apical and basal dendrites
One of the most striking features of neocortical anatomy is the presence of extensive top-
down projections into primary sensory areas. Notably, many of these top-down projections …
down projections into primary sensory areas. Notably, many of these top-down projections …
Perception and propagation of activity through the cortical hierarchy is determined by neural variability
The brains of higher organisms are composed of anatomically and functionally distinct
regions performing specialised tasks; but regions do not operate in isolation. Orchestration …
regions performing specialised tasks; but regions do not operate in isolation. Orchestration …
Structured flexibility in recurrent neural networks via neuromodulation
The goal of theoretical neuroscience is to develop models that help us better understand
biological intelligence. Such models range broadly in complexity and biological detail. For …
biological intelligence. Such models range broadly in complexity and biological detail. For …
Task adaption by biologically inspired stochastic comodulation
Brain representations must strike a balance between generalizability and adaptability.
Neural codes capture general statistical regularities in the world, while dynamically …
Neural codes capture general statistical regularities in the world, while dynamically …
Propagation of activity through the cortical hierarchy and perception are determined by neural variability
Brains are composed of anatomically and functionally distinct regions performing
specialized tasks, but regions do not operate in isolation. Orchestration of complex …
specialized tasks, but regions do not operate in isolation. Orchestration of complex …