A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

[HTML][HTML] Neuropathic pain: from mechanisms to treatment

NB Finnerup, R Kuner, TS Jensen - Physiological reviews, 2020 - journals.physiology.org
Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments

E Gambeta, JG Chichorro, GW Zamponi - Molecular pain, 2020 - journals.sagepub.com
The trigeminal nerve (V) is the fifth and largest of all cranial nerves, and it is responsible for
detecting sensory stimuli that arise from the craniofacial area. The nerve is divided into three …

The link between depression and chronic pain: neural mechanisms in the brain

J Sheng, S Liu, Y Wang, R Cui, X Zhang - Neural plasticity, 2017 - Wiley Online Library
Chronic pain, as a stress state, is one of the critical factors for determining depression, and
their coexistence tends to further aggravate the severity of both disorders. Unfortunately …

Central neuropathic pain

J Rosner, DC de Andrade, KD Davis… - Nature Reviews …, 2023 - nature.com
Central neuropathic pain arises from a lesion or disease of the central somatosensory
nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related …

Etiology and pharmacology of neuropathic pain

SRA Alles, PA Smith, LL Isom - Pharmacological reviews, 2018 - Elsevier
Injury to or disease of the nervous system can invoke chronic and sometimes intractable
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …

Cannabis and pain: a clinical review

KP Hill, MD Palastro, B Johnson… - … and cannabinoid research, 2017 - liebertpub.com
Introduction: Cannabis has been used for medical purposes across the world for centuries.
As states and countries implement medical and recreational cannabis policies, increasing …

Pharmacotherapy for neuropathic pain: a review

D Fornasari - Pain and therapy, 2017 - Springer
Neuropathic pain, comprising a range of heterogeneous conditions, is often severe and
difficult to manage, and this may result in a chronic condition that negatively affects the …

Neuropathic pain: From actual pharmacological treatments to new therapeutic horizons

M Thouaye, I Yalcin - Pharmacology & Therapeutics, 2023 - Elsevier
Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Effect of perioperative gabapentin on postoperative pain resolution and opioid cessation in a mixed surgical cohort: a randomized clinical trial

J Hah, SC Mackey, P Schmidt, R McCue… - JAMA …, 2018 - jamanetwork.com
Importance Guidelines recommend using gabapentin to decrease postoperative pain and
opioid use, but significant variation exists in clinical practice. Objective To determine the …