Small-angle X-ray and neutron scattering

CM Jeffries, J Ilavsky, A Martel, S Hinrichs… - Nature Reviews …, 2021 - nature.com
Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …

Small-angle X-ray scattering studies of enzymes

AS Byer, X Pei, MG Patterson, N Ando - Current opinion in chemical biology, 2023 - Elsevier
Enzyme function requires conformational changes to achieve substrate binding, domain
rearrangements, and interactions with partner proteins, but these movements are difficult to …

Atomistic structure of the SARS-CoV-2 pseudoknot in solution from SAXS-driven molecular dynamics

W He, J San Emeterio, MT Woodside… - Nucleic acids …, 2023 - academic.oup.com
Abstract SARS-CoV-2 depends on− 1 programmed ribosomal frameshifting (− 1 PRF) to
express proteins essential for its replication. The RNA pseudoknot stimulating− 1 PRF is …

Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade

AA Burnim, MA Spence, D Xu, CJ Jackson, N Ando - Elife, 2022 - elifesciences.org
Ribonucleotide reductases (RNRs) are used by all free-living organisms and many viruses
to catalyze an essential step in the de novo biosynthesis of DNA precursors. RNRs are …

[PDF][PDF] BioXTAS RAW 2: new developments for a free open-source program for small-angle scattering data reduction and analysis

JB Hopkins - Journal of applied crystallography, 2024 - journals.iucr.org
BioXTAS RAW is a free open-source program for reduction, analysis and modelling of
biological small-angle scattering data. Here, the new developments in RAW version 2 are …

EFAMIX, a tool to decompose inline chromatography SAXS data from partially overlapping components

PV Konarev, MA Graewert, CM Jeffries… - Protein …, 2022 - Wiley Online Library
Small‐angle X‐ray scattering (SAXS) is an established technique for structural analysis of
biological macromolecules in solution. During the last decade, inline chromatography …

Microsecond dynamics control the HIV-1 envelope conformation

AL Bennett, R Edwards, I Kosheleva, C Saunders… - Science …, 2024 - science.org
The HIV-1 Envelope (Env) glycoprotein facilitates host cell fusion through a complex series
of receptor-induced structural changes. Although remarkable progress has been made in …

Size exclusion chromatography coupled small angle X-ray scattering with tandem multiangle light scattering at the SIBYLS beamline

DJ Rosenberg, GL Hura, M Hammel - Methods in Enzymology, 2022 - Elsevier
Small-angle X-ray Scattering (SAXS) has been a versatile technique for studying
biomolecules in solution for several decades now. Developments in SAXS techniques that …

Advances, Applications, and Perspectives in Small‐Angle X‐ray Scattering of RNA

JN Tants, A Schlundt - Chembiochem, 2023 - Wiley Online Library
RNAs exhibit a plethora of functions far beyond transmitting genetic information. Often, RNA
functions are entailed in their structure, be it as a regulatory switch, protein binding site, or …

Perspectives on solution-based small angle X-ray scattering for protein and biological macromolecule structural biology

ASA Mohammed, D Soloviov… - Physical Chemistry …, 2024 - pubs.rsc.org
Small-angle X-rays scattering (SAXS) is used to extract structural information from a wide
variety of non-crystalline samples in different fields (eg, materials science, physics …