Giardia duodenalis captured the attention of Leeuwenhoek in 1681 while he was examining
his own diarrheal stool, but, ironically, it did not really gain attention as a human pathogen …

Genetic variation is the major mechanism behind adaptation and evolutionary change. As
most proteins operate through interactions with other proteins, changes in protein complex …

Over half of mitochondrial proteins are imported from the cytosol via the pre-sequence
pathway, controlled by the TOM complex in the outer membrane and the TIM23 complex in …

Mitochondria import nearly all of their approximately 1,000–2,000 constituent proteins from
the cytosol across their double-membrane envelope,,,–. Genetic and biochemical studies …

Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters,
which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway …

The evolution of mitochondrial protein import and the systems that mediate it marks the
boundary between the endosymbiotic ancestor of mitochondria and a true organelle that is …

Metamonads are a diverse group of heterotrophic microbial eukaryotes adapted to living in
hypoxic environments. All metamonads but one harbour metabolically altered …

The notion that mitochondria cannot be lost was shattered with the report of an oxymonad
Monocercomonoides exilis, the first eukaryote arguably without any mitochondrion. Yet …

This review is dedicated to the 50th anniversary of the discovery of hydrogenosomes by
Miklós Müller and Donald Lindmark, which we will celebrate the following year. It was a long …

The loss of mitochondria in oxymonad protists has been associated with the redirection of
the essential Fe-S cluster assembly to the cytosol. Yet as our knowledge of diverse free …