Nano-delivery systems for food bioactive compounds in cancer: Prevention, therapy, and clinical applications

IRS Vieira, CA Conte-Junior - Critical Reviews in Food Science …, 2024 - Taylor & Francis
Bioactive compounds represent a broad class of dietary metabolites derived from fruits and
vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer …

Brassica‐derived isothiocyanates as anticancer therapeutic agents and their nanodelivery

D Rizwan, FA Masoodi - Phytotherapy Research, 2024 - Wiley Online Library
The isothiocyanates (ITCs) derived from the precursor glucosinolate molecules present in
Brassica vegetables are bioactive organo‐sulfur compounds with numerous …

Anticarcinogenic effects of isothiocyanates on hepatocellular carcinoma

Y Zhang, H Huang, L Jin, S Lin - International Journal of Molecular …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer,
accounting for about 90% of cases. Sorafenib, lenvatinib, and the combination of …

Iberverin exhibits antineoplastic activities against human hepatocellular carcinoma via DNA damage-mediated cell cycle arrest and mitochondrial-related apoptosis

Y Zhang, J Du, L Jin, L Pan, X Yan, S Lin - Frontiers in Pharmacology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the malignant tumors with high incidence and
mortality rates in the world. Isothiocyanates (ITCs), bioactive substances present primarily in …

[HTML][HTML] Isothiocyanates in medicine: A comprehensive review on phenylethyl-, allyl-, and benzyl-isothiocyanates

CC Hoch, M Shoykhet, T Weiser, L Griesbaum… - Pharmacological …, 2024 - Elsevier
In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from
Brassicaceae vegetables and herbs, have gained significant attention within the biomedical …

Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis by reducing fungal load and inhibiting Mincle signal pathway

W Yi, L Gu, Y Wang, J Lin, L Zhang, Q Wang… - Frontiers in …, 2023 - frontiersin.org
Aspergillus fumigatus keratitis is a potential blinding disease associated with A. fumigatus
invasion and excessive inflammatory response. Benzyl isothiocyanate (BITC) is a secondary …

Targeting Peroxisome Proliferator-Activated Receptor-β/δ, Reactive Oxygen Species and Redox Signaling with Phytocompounds for Cancer Therapy

C Kaur, SK Sahu, K Bansal, LK DeLiberto… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Peroxisome proliferator-activated receptors (PPARs) have a moderately
preserved amino-terminal domain, an extremely preserved DNA-binding domain, an integral …

DNA damage response proteins in canine cancer as potential research targets in comparative oncology

B Hernández‐Suárez, DA Gillespie… - Veterinary and …, 2022 - Wiley Online Library
The DNA damage response (DDR) is a complex signal transduction network that is activated
when endogenous or exogenous genotoxins damage or interfere with the replication of …

[Retracted] Targeting AraC‐Resistant Acute Myeloid Leukemia by Dual Inhibition of CDK9 and Bcl‐2: A Systematic Review and Meta‐Analysis

L Li, C Han, X Yu, J Shen, Y Cao - Journal of Healthcare …, 2022 - Wiley Online Library
Purpose. This study aims to determine the influence of targeting araC‐resistant acute
myeloid leukemia by dual inhibition cyclin‐dependent protein kinase (CDK9) and B‐cell …

[HTML][HTML] Oxidative Stress in Canine Diseases: A Comprehensive Review

PM Blanca, FR María Luisa, M Guadalupe, CL Fátima - Antioxidants, 2024 - mdpi.com
Oxidative stress (OS), defined as a disruption in redox balance favoring oxidants, has
emerged as a major contributor to numerous diseases in human and veterinary medicine …