Chemistry and pharmacology of bergenin or its derivatives: A promising molecule

ZM Salimo, MN Yakubu, EL da Silva, ACG de Almeida… - Biomolecules, 2023 - mdpi.com
Bergenin is a glycosidic derivative of trihydroxybenzoic acid that was discovered in 1880 by
Garreau and Machelart from the rhizomes of the medicinal plant Bergenia crassifolia …

Diversity, pharmacology and synthesis of bergenin and its derivatives: Potential materials for therapeutic usages

GB Bajracharya - Fitoterapia, 2015 - Elsevier
Bergenin, a natural secondary metabolite, has been isolated from different parts of a number
of plants. It is one of active ingredients in herbal and Ayurvedic formulations. It exhibits …

Bergenin Plays an Anti-Inflammatory Role via the Modulation of MAPK and NF-κB Signaling Pathways in a Mouse Model of LPS-Induced Mastitis

X Gao, M Guo, Z Zhang, T Wang, Y Cao, N Zhang - Inflammation, 2015 - Springer
Mastitis is a major disease in humans and other animals and is characterized by mammary
gland inflammation. It is a major disease of the dairy industry. Bergenin is an active …

Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime

M Imran, MR Shah, F Ullah, S Ullah, AMA Elhissi… - International Journal of …, 2016 - Elsevier
This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant
synthesized and characterized in our laboratory for increased oral bioavailability of …

The natural product bergenin ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NF-kappaB activition

S Yang, Z Yu, L Wang, T Yuan, X Wang… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Bergenin, an active constituent of the plants of the genus
Bergenia, was reported to have anti-inflammatory effects in the treatment of chronic …

[HTML][HTML] Oxidative stress and inflammation

S Soomro - Open Journal of Immunology, 2019 - scirp.org
Inflammation is a part of the complex biological response of vascular tissues to harmful
stimuli. Debilitating diseases such as atherosclerosis, rheumatoid arthritis, and even cancer …

Bergenin loaded gum xanthan stabilized silver nanoparticles suppress synovial inflammation through modulation of the immune response and oxidative stress in …

K Rao, T Roome, S Aziz, A Razzak, G Abbas… - Journal of Materials …, 2018 - pubs.rsc.org
Bergenin (BG) is a naturally occurring C-glycoside with demonstrated anti-arthritic potential.
Its therapeutic efficacy is compromised due to its lower absorption and instability at neutral …

Regioselective synthesis of 3, 4-disubstituted isocoumarins through the Pd-catalyzed annulation of 2-iodoaromatic acids with ynamides

H Liu, Y Yang, J Wu, XN Wang, J Chang - Chemical Communications, 2016 - pubs.rsc.org
A Pd (0)-catalyzed annulation reaction of ynamides is described for the efficient synthesis of
3, 4-disubstituted isocoumarins. This novel methodology allows for the concomitant …

Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of levofloxacin

M Imran, MR Shah, F Ullah, S Ullah, AMA Elhissi… - Drug Delivery, 2016 - Taylor & Francis
Context: Vesicular systems have attracted great attention in drug delivery because of their
amphiphilicity, biodegradability, non-toxicity and potential for increasing drug bioavailability …

HPLC Analysis, Optimization of Extraction Conditions and Biological Evaluation of Corylopsis coreana Uyeki Flos

JH Seo, JE Kim, JH Shim, G Yoon, MA Bang, CS Bae… - Molecules, 2016 - mdpi.com
A method for the separation and quantification of three flavonoids and one isocoumarin by
reverse-phase high performance liquid chromatography (HPLC) has been developed and …