γδ T cells: origin and fate, subsets, diseases and immunotherapy

Y Hu, Q Hu, Y Li, L Lu, Z Xiang, Z Yin… - … and Targeted Therapy, 2023 - nature.com
The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Dendritic cells and macrophages in the pathogenesis of psoriasis

M Kamata, Y Tada - Frontiers in immunology, 2022 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
This disease impairs patients' quality of life enormously. Pathological findings demonstrate …

Skin barrier dysregulation in psoriasis

A Orsmond, L Bereza-Malcolm, T Lynch… - International journal of …, 2021 - mdpi.com
The skin barrier is broadly composed of two elements—a physical barrier mostly localised in
the epidermis, and an immune barrier localised in both the dermis and epidermis. These two …

[HTML][HTML] Mouse models of psoriasis: a comprehensive review

RS Gangwar, JE Gudjonsson, NL Ward - Journal of Investigative …, 2022 - Elsevier
The use of preclinical animal models of psoriasis has significantly increased over the last
three decades, with each model having unique strengths and limitations. Some models …

Dendritic cells: The driver of psoriasis

AO Wang, YP Bai - The Journal of dermatology, 2020 - Wiley Online Library
Psoriasis is a chronic skin inflammatory disorder, the immune mechanism of which has been
profoundly elucidated in the past few years. The dominance of the interleukin (IL)‐23/IL‐17 …

Dietary carbohydrates and lipids in the pathogenesis of leaky gut syndrome: An overview

A Binienda, A Twardowska, A Makaro… - International journal of …, 2020 - mdpi.com
This review summarizes the recent knowledge on the effects of dietary carbohydrates and
lipids on the pathophysiology of leaky gut syndrome (LGS). Alterations in intestinal barrier …

Mechanics of the stomach: A review of an emerging field of biomechanics

S Brandstaeter, SL Fuchs, RC Aydin… - GAMM …, 2019 - Wiley Online Library
Mathematical and computational modeling of the stomach is an emerging field of
biomechanics where several complex phenomena, such as gastric electrophysiology, fluid …

Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory

LC Chan, M Rossetti, LS Miller… - Proceedings of the …, 2018 - National Acad Sciences
Staphylococcus aureus is the leading cause of skin and skin structure infection (SSSI), a
primary portal of entry for invasive infection. Our prior studies discovered a role for protective …

The Immunology of Psoriasis—Current Concepts in Pathogenesis

I Sieminska, M Pieniawska, TM Grzywa - Clinical Reviews in Allergy & …, 2024 - Springer
Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-
remitting course. The last decades of intense research uncovered a pathological network of …

The kinase p38α functions in dendritic cells to regulate Th2-cell differentiation and allergic inflammation

M Han, J Ma, S Ouyang, Y Wang, T Zheng… - Cellular & molecular …, 2022 - nature.com
Dendritic cells (DCs) play a critical role in controlling T helper 2 (Th2) cell-dependent
diseases, but the signaling mechanism that triggers this function is not fully understood. We …