Atropisomerism is a stereochemical behavior portrayed by three-dimensional molecules that
bear rotationally restricted σ bond. Akin to the well-represented point-chiral molecules …

Hypervalent aryliodoumiums are intensively investigated as arylating agents. They are
excellent surrogates to aryl halides, and moreover they exhibit better reactivity, which allows …

Atropisomers beyond the C–C axis (denoted as X–Y herein) are important addition to the
repertoire of axially chiral compounds, which have received much attention in recent years …

Conspectus Arising from the restricted rotation of a single bond caused by steric or
electronic effects, atropisomerism is one of the few fundamental categories for molecules to …

Atropisomeric C–N compounds belong to an important class of axially chiral compounds.
However, whereas the asymmetric synthesis of biaryl atropisomers have been well …

The development of catalytic enantioselective transformations, enabling the construction of
complex molecular scaffolds from simple precursors, has been a long-standing challenge in …

The atroposelective synthesis of atropisomers with vicinal diaxes remains rare and
challenging, due to the steric influence between the two axes and their unique topology …

The first catalytic asymmetric synthesis of N–N axially chiral compounds has been
accomplished via a quinidine catalyzed N-allylic alkylation reaction. These N–N axially …

The efficient stereoselective synthesis of conjugated dienes, especially those with axial
chirality, remains a great challenge. Herein, we report the highly atroposelective synthesis of …

Catalytic dynamic kinetic asymmetric transformation (DyKAT) provides a powerful tool to
access chiral stereoisomers from racemic substrates. Such transformation has been widely …