Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Autophagy is an evolutionarily conserved mechanism by which cytoplasmic elements are
degraded intracellularly. Autophagy has also emerged as a major regulator of cardiac …

Macroautophagy/autophagy has profound implications for aging. However, the true features
of autophagy in the progression of aging remain to be clarified. In the present study, we …

Myofibroblasts play an important role in fibrogenesis. Hepatic stellate cells are the main
precursors of myofibroblasts. Cellular senescence is the terminal cell fate in which …

Phosphoinositide 3-kinases (PI3Ks) control many important aspects of immune cell
development, differentiation, and function. Mammals have eight PI3K catalytic subunits that …

Silver nanoparticles (AgNPs), embedded into a specific polysaccharide (EPS), were
biogenerated by Klebsiella oxytoca DSM 29614 under aerobic (AgNPs-EPSaer) and …

Autophagy is a conserved quality-control pathway that degrades cytoplasmic contents in
lysosomes. Autophagy degrades lipid droplets through a process termed lipophagy …

Programmed cell death (PCD) is the universal process that maintains cellular homeostasis
and regulates all living systems' development, health and disease. Out of all, apoptosis is …

There is currently no approved neuroprotective pharmacotherapy for acute conditions such
as stroke and cerebral asphyxia. One of the reasons for this may be the multiplicity of cell …

Remodeling of cytoskeleton structures, such as microtubule assembly, is believed to be
crucial for growth cone initiation and regrowth of injured axons. Autophagy plays important …