[HTML][HTML] Macrophage plasticity and atherosclerosis therapy

P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

[HTML][HTML] Macrophage polarization states in atherosclerosis

J Wu, S He, Z Song, S Chen, X Lin, H Sun… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis, a chronic inflammatory condition primarily affecting large and medium
arteries, is the main cause of cardiovascular diseases. Macrophages are key mediators of …

[HTML][HTML] DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

AB Herman, D Tsitsipatis, C Anerillas… - The Journal of …, 2023 - Am Soc Clin Investig
Senescent vascular smooth muscle cells (VSMCs) accumulate in the vasculature with age
and tissue damage and secrete factors that promote atherosclerotic plaque vulnerability and …

Matrix stiffness regulates macrophage polarization in atherosclerosis

Y Wang, R Shi, R Zhai, S Yang, T Peng, F Zheng… - Pharmacological …, 2022 - Elsevier
Atherosclerosis is a chronic inflammatory disease and the pathological basis of many fatal
cardiovascular diseases. Macrophages, the main inflammatory cells in atherosclerotic …

[HTML][HTML] Challenging the paradigm: anti-inflammatory interleukins and angiogenesis

AM Peluzzo, MV Autieri - Cells, 2022 - mdpi.com
Angiogenesis is a vital biological process, and neovascularization is essential for the
development, wound repair, and perfusion of ischemic tissue. Neovascularization and …

[HTML][HTML] Novel insight on the role of Macrophages in atherosclerosis: Focus on polarization, apoptosis and efferocytosis

Y Xie, H Chen, P Qu, X Qiao, L Guo, L Liu - International …, 2022 - Elsevier
Atherosclerosis (AS) is the main pathological basis of cardiovascular diseases, which is
mainly characterized by lipid deposition and inflammatory response. Macrophages (MΦ), as …

The role of interleukin-10 family members in cardiovascular diseases

S Xu, J Zhang, J Liu, J Ye, Y Xu, Z Wang, J Yu… - International …, 2021 - Elsevier
Abstract Interleukin (IL)-10 cytokine family members, including IL-10, IL-19, IL-20, IL-22, IL-
24, IL-26 and the distantly related IL-28A, IL-28B, and IL-29, play critical roles in the …

Interleukin 22 promotes blood pressure elevation and endothelial dysfunction in angiotensin II–treated mice

J Ye, Q Ji, J Liu, L Liu, Y Huang, Y Shi… - Journal of the …, 2017 - Am Heart Assoc
Background CD 4+ T helper (Th) cells, including Th1, Th2, and Th17 cells, play critical roles
in angiotensin II–induced hypertension. Th22 cells, a novel subset of Th cells, take part in …

[HTML][HTML] The crosstalk of ABCA1 and ANXA1: A potential mechanism for protection against atherosclerosis

X Shen, S Zhang, Z Guo, D Xing, W Chen - Molecular Medicine, 2020 - Springer
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic
inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol …

Regulation of stress granule formation by inflammation, vascular injury, and atherosclerosis

AB Herman, M Silva Afonso, SE Kelemen… - … , and vascular biology, 2019 - Am Heart Assoc
Objective: Stress granules (SGs) are dynamic cytoplasmic aggregates containing mRNA,
RNA-binding proteins, and translation factors that form in response to cellular stress. SGs …