Chitosan-based nanoparticles against bacterial infections

S Rashki, K Asgarpour, H Tarrahimofrad… - Carbohydrate …, 2021 - Elsevier
Chitosan nanomaterials have become a hot topic in biomedicine due to exerting
antimicrobial effects with interestingly high levels of biodegradability and biocompatibility …

[HTML][HTML] Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria

G Batoni, G Maisetta, S Esin - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Biofilm-associated infections represent one of the major threats of modern medicine. Biofilm-
forming bacteria are encased in a complex mixture of extracellular polymeric substances …

Chitosan nanoparticles loaded with the antimicrobial peptide temporin B exert a long-term antibacterial activity in vitro against clinical isolates of Staphylococcus …

AM Piras, G Maisetta, S Sandreschi… - Frontiers in …, 2015 - frontiersin.org
Nowadays, the alarming rise in multidrug-resistant microorganisms urgently demands for
suitable alternatives to current antibiotics. In this regard, antimicrobial peptides (AMPs) have …

Advanced topical drug delivery system for the management of vaginal candidiasis

HS Johal, T Garg, G Rath, AK Goyal - Drug delivery, 2016 - Taylor & Francis
Vaginal candidiasis or vulvovaginal candidiasis (VC) is a common mucosal infection of
vagina, mainly caused by Candida species. The major symptoms of VC are dyspareunia …

pH dependent antimicrobial peptides and proteins, their mechanisms of action and potential as therapeutic agents

E Malik, SR Dennison, F Harris, DA Phoenix - Pharmaceuticals, 2016 - mdpi.com
Antimicrobial peptides (AMPs) are potent antibiotics of the innate immune system that have
been extensively investigated as a potential solution to the global problem of infectious …

Development of novel ultrashort antimicrobial peptide nanoparticles with potent antimicrobial and antibiofilm activities against multidrug-resistant bacteria

A Almaaytah, GK Mohammed… - Drug design …, 2017 - Taylor & Francis
Conventional antibiotics are facing strong microbial resistance that has recently reached
critical levels. This situation is leading to significantly reduced therapeutic potential of a huge …

Natural and synthetic peptides with antifungal activity

T Ciociola, L Giovati, S Conti, W Magliani… - Future medicinal …, 2016 - Taylor & Francis
In recent years, the increase of invasive fungal infections and the emergence of antifungal
resistance stressed the need for new antifungal drugs. Peptides have shown to be good …

Therapeutic potential of hepcidin− the master regulator of iron metabolism

D Vyoral, J Petrak - Pharmacological research, 2017 - Elsevier
Iron is an essential biogenic element for both prokaryotic and eukaryotic cells. In humans
iron is present in hundreds of different metalloproteins. The peptide hormone hepcidin …

Antifungal activity of cathelicidin peptides against planktonic and biofilm cultures of Candida species isolated from vaginal infections

M Scarsini, L Tomasinsig, A Arzese, F D'Este, D Oro… - Peptides, 2015 - Elsevier
Vulvovaginal candidiasis (VVC) is a frequent gynecological condition caused by Candida
albicans and a few non-albicans Candida spp. It has a significant impact on the quality of life …

Nutritional immunity and fungal pathogenesis: the struggle for micronutrients at the host–pathogen interface

D Malavia, A Crawford, D Wilson - Advances in microbial physiology, 2017 - Elsevier
All living organisms require certain micronutrients such as iron, zinc, manganese and
copper for cellular function and growth. For human pathogens however, the maintenance of …