It has been known for 50 years that transaminase activity increases in patients with acute
myocardial infarction. With the development of creatine kinase (CK), biomarkers of cardiac …

This article has been copublished in the April issue of Clinical Chemistry (Volume 53,
Number 4, 2007). 1 Brigham and Women's Hospital, Harvard University, Boston, MA. 2 …

Background In patients with acute coronary syndromes, it is desirable to identify a sensitive
serum marker that is closely related to the degree of myocardial damage, provides …

BACKGROUND Levels of MBCK can be increased in patients with skeletal muscle injury or
renal failure in the absence of myocardial injury, causing diagnostic confusion. This study …

Troponin is a widely used biomarker in patients with cardiac disease. The use of troponin is
well established in patients with suspected acute myocardial infarction (AMI), but troponin …

Background Endomyocardial biopsy is currently the standard method used to diagnose
myocarditis. However, it is invasive and has a low diagnostic yield. Because the histological …

OBJECTIVES We investigated the role of cardiac troponin I (cTnI) in patients with aggressive
malignancies treated with high-dose chemotherapy (HDC). BACKGROUND High dose …

M odern medical practice requires rapid decisions. Patients must be triaged faster, treated
more expeditiously, and discharged earlier. Diagnostic tests used to evaluate patients with …

Acute myocardial infarction or myocardial infarction (MI) is a major health problem, due to
diminished flow of blood to the heart, leads to higher rates of mortality and morbidity. Data …

Cardiac troponin I (cTnI) is well-known as a promising biomarker for the early diagnosis of
acute myocardial infarction (AMI). In this work, single-stranded DNA aptamers against cTnI …