Fentanyl is a powerful opioid anesthetic and analgesic, the use of which has caused an
increasing public health threat in the United States and elsewhere. Fentanyl was initially …

Fentanyl is a potent synthetic opioid used as a narcotic analgesic supplement in general
and regional anesthesia as well as in management of persistent, severe chronic pain …

Abstract Background British Columbia, Canada, is experiencing a public health emergency
related to opioid overdoses driven by consumption of street drugs contaminated with illicitly …

Background The overdose epidemic has been exacerbated by a dramatic increase in
deaths involving illicitly manufactured fentanyl (IMF). Drug checking is a novel strategy to …

A chief coroner investigation in British Columbia, Canada, identified an “inordinately high
number” of drug-related deaths related to a “very real and very serious” drug problem, and …

Background Although oral opioid agonist therapies (OATs), buprenorphine and methadone,
are effective first-line treatments, OAT remains largely underutilized due to low retention …

Background In 2016, drug overdose deaths exceeded 64,000 in the United States, driven by
a sixfold increase in deaths attributable to illicitly manufactured fentanyl. Rapid fentanyl test …

Introduction The illicit opioid supply in the US is increasingly adulterated with fentanyl. As
such, persons with opioid use disorder (OUD) may be regularly exposed to fentanyl …

Background Overdose deaths involving stimulants and opioids simultaneously have raised
the specter of widespread contamination of the stimulant supply with fentanyl. Methods We …

Background As the overdose crisis in Canada continues to escalate in severity, novel
interventions and programs are required. Safer Supply programs offer pharmaceutical-grade …