Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

M Wu, LJ Hill, LE Downie, HR Chinnery - Progress in Retinal and Eye …, 2022 - Elsevier
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

[HTML][HTML] Corneal confocal microscopy: a biomarker for diabetic peripheral neuropathy

IN Petropoulos, G Ponirakis, M Ferdousi, S Azmi… - Clinical …, 2021 - Elsevier
Purpose Diagnosing early diabetic peripheral neuropathy remains a challenge due to
deficiencies in currently advocated end points. The cornea is densely innervated with small …

Limbal epithelial stem cells in the diabetic cornea

L Nureen, N Di Girolamo - Cells, 2023 - mdpi.com
Continuous replenishment of the corneal epithelium is pivotal for maintaining optical
transparency and achieving optimal visual perception. This dynamic process is driven by …

Obese mice with dyslipidemia exhibit meibomian gland hypertrophy and alterations in meibum composition and aqueous tear production

EA Osae, T Bullock, M Chintapalati… - International Journal of …, 2020 - mdpi.com
Background: Dyslipidemia may be linked to meibomian gland dysfunction (MGD) and
altered meibum lipid composition. The purpose was to determine if plasma and meibum …

Association of serum lipid level with meibum biosynthesis and meibomian gland dysfunction: a review

YS Yoo, SK Park, HS Hwang, HS Kim, R Arita… - Journal of clinical …, 2022 - mdpi.com
The primary role of meibomian glands (MGs) is to actively synthesize and secret lipids and
proteins spread onto the tear film, and the glandular lipids promote tear stability, prevent …

Ocular surface physiology and aqueous tear secretion in cats of diverse cephalic conformations

J Oksa‐Minaļto, DJ Maggs, J Akimova… - Veterinary …, 2023 - Wiley Online Library
Objective To describe normative ocular surface and aqueous tear testing data for cats of
various cephalic conformation. Animals studied Fifty‐three healthy adult cats (11 British …

High-fat nutritional challenge reshapes circadian signatures in murine extraorbital lacrimal glands

S Zou, X Jiao, J Liu, D Qi, X Pei, D Lu… - … & Visual Science, 2022 - iovs.arvojournals.org
Purpose: A high-fat diet (HFD) increases the risk of developing many systemic diseases;
however, the effects of high fat intake on lacrimal gland functions and the molecular …

High fat diet induced gut dysbiosis alters corneal epithelial injury response in mice

K Kang, Q Zhou, L McGinn, T Nguyen, Y Luo… - The ocular …, 2022 - Elsevier
Purpose Commensal microbiome secretes various metabolites that can exert important
effects on the host immunity and inflammation and can alter cellular functions. However, little …

An epithelial abrasion model for studying corneal wound healing

PK Akowuah, A De La Cruz, CW Smith… - JoVE (Journal of …, 2021 - jove.com
The cornea is critical for vision, accounting for about two-thirds of the refractive power of the
eye. Crucial to the role of the cornea in vision is its transparency. However, due to its …

A low-fat/sucrose diet rich in complex carbohydrates reverses high-fat/sucrose diet-induced corneal dysregulation

PK Akowuah, C Lema, RE Rumbaut… - International Journal of …, 2023 - mdpi.com
High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs
corneal wound healing. While changing to a diet with a low fat/sugar composition and …