Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Alzheimer's disease (AD) is a multifactorial and fatal neurodegenerative disorder for which
the mechanisms leading to profound neuronal loss are incompletely recognized. MicroRNAs …

Major depressive disorder (MDD) is predicted to be the second leading cause of global
disease burden by 2030. A large number of MDD patients do not respond to the currently …

As human life expectancy increases, cognitive decline and memory impairment threaten
independence and quality of life. Therefore, finding prevention and treatment strategies for …

Aims/hypothesis MicroRNAs are key regulators of gene expression involved in health and
disease. The goal of our study was to investigate the global changes in beta cell microRNA …

MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that play important
roles in the development and functions of the brain. Extensive studies have revealed critical …

Highlights•miRNAs and RISC are located near synapses.•miRNAs regulate local protein
synthesis in dendrites and axons.•miRNAs play important roles in synapse development and …

Effective treatments for neurodegenerative diseases need to be developed. MiR132 is
abundantly expressed in the brain, and it modulates neuron morphology and plays a key …

MicroRNAs, the non-coding single-stranded RNA of 19–25 nucleotides are emerging as
robust players of gene regulation. Plethora of evidences support that the ability of …