Phytochemistry and biological activity of medicinal plants in wound healing: an overview of current research

S Vitale, S Colanero, M Placidi, G Di Emidio, C Tatone… - Molecules, 2022 - mdpi.com
Wound healing is a complicated process, and the effective management of wounds is a
major challenge. Natural herbal remedies have now become fundamental for the …

Cellular and molecular mechanisms of repair in acute and chronic wound healing

P Martin, R Nunan - British Journal of Dermatology, 2015 - academic.oup.com
A considerable understanding of the fundamental cellular and molecular mechanisms
underpinning healthy acute wound healing has been gleaned from studying various animal …

[HTML][HTML] Role of matrix metalloproteinase in wound healing

M Kandhwal, T Behl, S Singh, N Sharma… - American journal of …, 2022 - ncbi.nlm.nih.gov
Matrix metalloproteinases (MMPs) are a group of endopeptidases that play a vital role in the
restoration of damaged skin. Through mediating various cellular events such as …

Vascular endothelial growth factor and angiogenesis in the regulation of cutaneous wound repair

KE Johnson, TA Wilgus - Advances in wound care, 2014 - liebertpub.com
Significance: Angiogenesis, the growth of new blood vessels from existing vessels, is an
important aspect of the repair process. Restoration of blood flow to damaged tissues …

Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing

NS Greaves, KJ Ashcroft, M Baguneid… - Journal of dermatological …, 2013 - Elsevier
Cutaneous wound healing ultimately functions to facilitate barrier restoration following injury-
induced loss of skin integrity. It is an evolutionarily conserved, multi-cellular, multi-molecular …

Oxygen in acute and chronic wound healing

S Schreml, RM Szeimies, L Prantl… - British Journal of …, 2010 - academic.oup.com
Oxygen is a prerequisite for successful wound healing due to the increased demand for
reparative processes such as cell proliferation, bacterial defence, angiogenesis and …

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

S Willenborg, T Lucas, G Van Loo… - Blood, The Journal …, 2012 - ashpublications.org
Monocytes/macrophages are critical in orchestrating the tissue-repair response. However,
the mechanisms that govern macrophage regenerative activities during the sequential …

Aloe vera: Ancient knowledge with new frontiers

DI Sánchez-Machado, J López-Cervantes… - Trends in Food Science …, 2017 - Elsevier
Background There are many plants with interesting pharmaceutical activities but Aloe vera is
probably the most applied medicinal plant worldwide. Since biblical times, aloe has been …

Cancer as an overhealing wound: an old hypothesis revisited

M Schäfer, S Werner - Nature reviews Molecular cell biology, 2008 - nature.com
What is the relationship between the wound-healing process and the development of
cancer? Malignant tumours often develop at sites of chronic injury, and tissue injury has an …

From inflammation to current and alternative therapies involved in wound healing

MB Serra, WA Barroso, NN Silva… - International journal …, 2017 - Wiley Online Library
Wound healing is a complex event that develops in three overlapping phases: inflammatory,
proliferative, and remodeling. These phases are distinct in function and histological …