Spotlight on GOT2 in Cancer Metabolism
SA Kerk, J Garcia-Bermudez, K Birsoy… - OncoTargets and …, 2023 - Taylor & Francis
GOT2 is at the nexus of several critical metabolic pathways in homeostatic cellular and
dysregulated cancer metabolism. Despite this, recent work has emphasized the remarkable …
dysregulated cancer metabolism. Despite this, recent work has emphasized the remarkable …
[HTML][HTML] PARP1 Characterization as a Potential Biomarker for BCR::ABL1 p190+ Acute Lymphoblastic Leukemia
CB Machado, EL da Silva, WAS Ferreira… - Cancers, 2023 - mdpi.com
Simple Summary Acute lymphoblastic leukemia (ALL) is the most common childhood cancer
and the presence of BCR:: ABL1 fusion in p190 isoform is a marker for worse prognosis …
and the presence of BCR:: ABL1 fusion in p190 isoform is a marker for worse prognosis …
[HTML][HTML] GLS and GOT2 as prognostic biomarkers associated with dendritic cell and immunotherapy response in breast cancer
R Yang, S Cheng, J Xiao, Y Pei, Z Zhu, J Zhang, J Feng… - Heliyon, 2024 - cell.com
Breast cancer is the females' most common cancer. Targeting the immune microenvironment
is a new and promising treatment method for breast cancer. Nevertheless, only a small …
is a new and promising treatment method for breast cancer. Nevertheless, only a small …
[HTML][HTML] Molecules at Play in Cancer
DA Iacobas - Current Issues in Molecular Biology, 2023 - mdpi.com
Despite its wide range of incidence, cancer can spontaneously occur in any part of the body
and invade regions other than the originally affected tissue. Extensive research conducted …
and invade regions other than the originally affected tissue. Extensive research conducted …
[HTML][HTML] Pan-cancer molecular signatures connecting aspartate transaminase (AST) to cancer prognosis, metabolic and immune signatures
Background Serum aspartate transaminase (sAST) level is used routinely in conjunction
with other clinical assays to assess liver health and disease. Increasing evidence suggests …
with other clinical assays to assess liver health and disease. Increasing evidence suggests …
Evaluation of aristolochic acid Ι nephrotoxicity in mice via 1H NMR quantitative metabolomics and network pharmacology approaches
LL Feng, Z Huang, YY Nong, BJ Guo… - Toxicology …, 2023 - academic.oup.com
Background Although many studies have shown that herbs containing aristolochic acids can
treat various human diseases, AAΙ in particular has been implicated as a nephrotoxic agent …
treat various human diseases, AAΙ in particular has been implicated as a nephrotoxic agent …
[HTML][HTML] PARP1 is differentially expressed in BCR-ABL p190+ ALL patient samples and targeting PARP inhibition induces cell death comparable to that of tyrosine …
CB Machado, WAS Ferreira, F Pessoa… - … , Transfusion and Cell …, 2023 - Elsevier
Objective BCR-ABL1 p190 translocation represents a worse prognosis for acute
lymphoblastic leukemia (ALL) patients, and development of new therapeutic approaches is …
lymphoblastic leukemia (ALL) patients, and development of new therapeutic approaches is …