Tissue repair and regeneration with endogenous stem cells

H Xia, X Li, W Gao, X Fu, RH Fang, L Zhang… - Nature Reviews …, 2018 - nature.com
In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics …

Hydrophilic surface functionalization of electrospun nanofibrous scaffolds in tissue engineering

B Niemczyk-Soczynska, A Gradys, P Sajkiewicz - Polymers, 2020 - mdpi.com
Electrospun polymer nanofibers have received much attention in tissue engineering due to
their valuable properties such as biocompatibility, biodegradation ability, appropriate …

Three-dimensional cell culture matrices: state of the art

J Lee, MJ Cuddihy, NA Kotov - Tissue engineering part B: reviews, 2008 - liebertpub.com
Traditional methods of cell growth and manipulation on 2-dimensional (2D) surfaces have
been shown to be insufficient for new challenges of cell biology and biochemistry, as well as …

Tuning the biomimetic behavior of scaffolds for regenerative medicine through surface modifications

NR Richbourg, NA Peppas… - Journal of tissue …, 2019 - Wiley Online Library
Tissue engineering and regenerative medicine rely extensively on biomaterial scaffolds to
support cell adhesion, proliferation, and differentiation physically and chemically in vitro and …

Biomimetic scaffolds for tissue engineering

TG Kim, H Shin, DW Lim - Advanced Functional Materials, 2012 - Wiley Online Library
Biomimetic scaffolds mimic important features of the extracellular matrix (ECM) architecture
and can be finely controlled at the nano‐or microscale for tissue engineering. Rational …

Application of alginate hydrogels for next-generation articular cartilage regeneration

W Liu, H Madry, M Cucchiarini - International Journal of Molecular …, 2022 - mdpi.com
The articular cartilage has insufficient intrinsic healing abilities, and articular cartilage
injuries often progress to osteoarthritis. Alginate-based scaffolds are attractive biomaterials …

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

DSW Benoit, MP Schwartz, AR Durney, KS Anseth - Nature materials, 2008 - nature.com
Cell–matrix interactions have critical roles in regeneration, development and disease. The
work presented here demonstrates that encapsulated human mesenchymal stem cells …

Macroscale delivery systems for molecular and cellular payloads

CJ Kearney, DJ Mooney - Nature materials, 2013 - nature.com
Macroscale drug delivery (MDD) devices are engineered to exert spatiotemporal control
over the presentation of a wide range of bioactive agents, including small molecules …

Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone

JH Chen, C Liu, L You, CA Simmons - Journal of biomechanics, 2010 - Elsevier
Bone tissue forms and is remodeled in response to the mechanical forces that it
experiences, a phenomenon described by Wolff's Law. Mechanically induced formation and …

Novel biodegradable chitosan–gelatin/nano-bioactive glass ceramic composite scaffolds for alveolar bone tissue engineering

M Peter, NS Binulal, SV Nair, N Selvamurugan… - Chemical engineering …, 2010 - Elsevier
Bioactive glass ceramic nanoparticles (nBGC) were synthesized by sol–gel process and
characterized using FTIR, TEM and XRD. Composite scaffolds of chitosan (CS)–gelatin (CG) …