Strigolactones, from plants to human health: achievements and challenges

V Dell'Oste, F Spyrakis, C Prandi - Molecules, 2021 - mdpi.com
Strigolactones (SLs) are a class of sesquiterpenoid plant hormones that play a role in the
response of plants to various biotic and abiotic stresses. When released into the …

Filling the Gap: Functional Clustering of ABC Proteins for the Investigation of Hormonal Transport in planta

L Borghi, J Kang, R de Brito Francisco - Frontiers in plant science, 2019 - frontiersin.org
Plant hormones regulate a myriad of plant processes, from seed germination to
reproduction, from complex organ development to microelement uptake. Much has been …

Development of strigolactones as novel autophagy/mitophagy inhibitors against colorectal cancer cells by blocking the autophagosome–lysosome fusion

ST Yang, JB Fan, TT Liu, S Ning, JH Xu… - Journal of Medicinal …, 2022 - ACS Publications
Inhibition of autophagy has been widely viewed as a promising strategy for anticancer
therapy. However, few effective and specific autophagy inhibitors have been reported …

[HTML][HTML] An ecotoxicological assessment of a strigolactone mimic used as the active ingredient in a plant biostimulant formulation

SJ Brooks, T Gomes, AC Almeida, M Christou… - Ecotoxicology and …, 2024 - Elsevier
A risk assessment on the aquatic toxicity of the plant biostimulant strigolactone mimic (2-(4-
methyl-5-oxo-2, 5-dihydro-furan-2-yloxy)-benzo [de] isoquinoline-1, 3-dione (SL-6) was …

Cytotoxicity of extracts and compounds isolated from Croton echioides in animal tumor cell (HTC)

I Vendruscolo, SRT Venturella, PA Bressiani… - Brazilian Journal of …, 2022 - SciELO Brasil
The search for compounds with anticancer effects is of paramount importance today due to
the high incidence of the disease. The Euphorbiaceae family is known for having …

Natural and synthetic anticancer epidrugs targeting the epigenetic integrator UHRF1

W Ashraf, T Ahmad, N Reynoird, A Hamiche, Y Mély… - Molecules, 2023 - mdpi.com
Cancer is one of the leading causes of death worldwide, and its incidence and mortality are
increasing each year. Improved therapeutic strategies against cancer have progressed, but …

Pharmacoepigenetic processors: epigenetic drugs, drug resistance, toxicoepigenetics, and nutriepigenetics

R Cacabelos, JC Carril, A Sanmartín, P Cacabelos - Pharmacoepigenetics, 2019 - Elsevier
The pharmacoepigenetic apparatus is integrated by gene clusters of different categories,
including (i) pathogenic genes involved in disease pathogenesis,(ii) mechanistic genes …

Strigolactones: phytohormones with promising biomedical applications

C Prandi, Y Kapulnik, H Koltai - European Journal of Organic …, 2021 - Wiley Online Library
Strigolactones are a class of carotenoid‐derived plant hormones, which impact many
functions of plant metabolism in response to environmental stress. They also act as …

GR24, a synthetic strigolactone analog, and light affect the organization of cortical microtubules in Arabidopsis hypocotyl cells

Y Krasylenko, G Komis, S Hlynska… - Frontiers in Plant …, 2021 - frontiersin.org
Strigolactones are plant hormones regulating cytoskeleton-mediated developmental events
in roots, such as lateral root formation and elongation of root hairs and hypocotyls. The latter …

[PDF][PDF] Strigol1/albumin/chitosan nanoparticles decrease cell viability, induce apoptosis and alter metabolomics profile in HepG2 cancer cell line

AL Al-Malki, A Bakkar, EA Huwait, EK Barbour… - Biomed …, 2021 - academia.edu
Hepatocellular carcinoma is one of the most common causes of cancer-related deaths
globally. Bioavailable, effective and safe therapeutic agents are urgently needed for cancer …