Mitochondria are best known for harboring pathways involved in ATP synthesis through the
tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding …

Key discoveries in aging research have been made possible with the use of model
organisms. Caenorhabditis elegans is a short-lived nematode that has become a well …

Introduction. Mitochondria supply cellular energy and are key regulators of intrinsic cell
death and consequently affect longevity. The nematode Caenorhabditis elegans is …

Chicoric acid, a hydroxycinnamic acid, has been reported to possess a variety of health
benefits, including antivirus, antioxidant, anti-inflammation, obesity prevention, and …

High-glycemic-index diets, as well as a sedentary lifestyle are considered as determinant
factors for the development of obesity, type 2 diabetes, and cardiovascular diseases in …

Beta‐amyloid (Aβ) accumulation in the brains of Alzheimer's disease (AD) patients leads to
mitochondrial dysfunction and ferroptosis in neurons. Voltage‐dependent anion channel 1 …

Chicoric acid is a dicaffeoyl ester with many bioactivities, including antioxidation,
antidiabetes, and anti-inflammation. A previous study reported that chicoric acid extended …

Vaccinia virus–related kinase (VRK) is an evolutionarily conserved nuclear protein kinase.
VRK-1, the single Caenorhabditis elegans VRK ortholog, functions in cell division and …

Advanced age is an independent risk factor for natural death and common diseases, such
as cardiovascular diseases, dementia, and cancers, which are life-threatening and cause …

Lifespan is a comprehensive indicator of health. Medium and long chain triacylglycerol
(MLCT) is an emerging functional product, while there are two types of MLCT (physical …