Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …

One of the hallmarks of cancer cells is increased energy requirements associated with the
higher rate of cellular proliferative activity. Metabolic changes in rapidly dividing cancer cells …

Hypoxia treatment enhances paracrine effect of mesenchymal stem cells (MSCs). The aim of
this study was to investigate whether exosomes from hypoxia-treated MSCs (ExoH) are …

The respiratory response to hypoxia in mammals develops from an inhibition of breathing
movements in utero into a sustained increase in ventilation in the adult. This ventilatory …

The use of mesenchymal stem-cells (MSC) in cell therapy has received considerable
attention because of their properties. These properties include high expansion and …

BACKGROUND microRNAs (miRNAs) are short, single-stranded RNAs that regulate gene
expression at the post-transcriptional level. Recent research has shown that miRNAs and …

ABSTRACT A keloid is defined as an overgrowth of the dense fibrous tissues that form
around a wound. Since they destroy the vascular network, keloid tissues often exhibit anoxic …

The heart is able to metabolize any substrate, depending on its availability, to satisfy its
energy requirements. Under normal physiological conditions, about 95% of ATP is produced …

Oxidative stress is the leading player in the onset and development of various diseases. The
Keap1-Nrf2 pathway is a pivotal antioxidant system that preserves the cells' redox balance. It …

Nickel compounds are environmental toxicants, prevalent in the atmosphere due to their
widespread use in several industrial processes, extensive consumption of nickel containing …