'Multi-omics' data integration: applications in probiotics studies

ID Kwoji, OA Aiyegoro, M Okpeku, MA Adeleke - npj Science of Food, 2023 - nature.com
The concept of probiotics is witnessing increasing attention due to its benefits in influencing
the host microbiome and the modulation of host immunity through the strengthening of the …

Targeting the microbiome-gut-brain axis for improving cognition in schizophrenia and major mood disorders: A narrative review

M Bioque, A González-Rodríguez… - Progress in Neuro …, 2021 - Elsevier
Cognitive impairment has been consistently found to be a core feature of serious mental
illnesses such as schizophrenia and major mood disorders (major depression and bipolar …

Probiotic Clostridium butyricum ameliorated motor deficits in a mouse model of Parkinson's disease via gut microbiota-GLP-1 pathway

J Sun, H Li, Y Jin, J Yu, S Mao, KP Su, Z Ling… - Brain, behavior, and …, 2021 - Elsevier
A connection between gut microbiota and Parkinson's disease (PD) indicates that dysbiosis
of the gut microbiota might represent a risk factor for PD. Microbiota-targeted interventions …

New insights into the relationship between gut microbiota and radiotherapy for cancer

Z Li, X Ke, D Zuo, Z Wang, F Fang, B Li - Nutrients, 2022 - mdpi.com
Cancer is the second most common cause of death among humans in the world, and the
threat that it presents to human health is becoming more and more serious. The …

Microfluidic-based multifunctional microspheres for enhanced oral co-delivery of probiotics and postbiotics

X Yang, W Nie, C Wang, Z Fang, L Shang - Biomaterials, 2024 - Elsevier
Probiotic-based therapies have shown great potential in the prevention and treatment of
many diseases by positively regulating intestinal flora homeostasis. However, the efficacy of …

Safety assessment of crude saponins from Chenopodium quinoa willd. husks: 90-day oral toxicity and gut microbiota & metabonomics study in rats

R Zhang, Q Zhai, Y Yu, X Li, F Zhang, Z Hou, Y Cao… - Food Chemistry, 2022 - Elsevier
The subchronic toxicity of saponins of Chenopodium quinoa Willd. husks in healthy adult
Sprague-Dawley (SD) rats was explored. Female and male rats were randomly divided into …

Probiotics exert protective effect against sepsis-induced cognitive impairment by reversing gut microbiota abnormalities

J Liu, Y Jin, H Li, J Yu, T Gong, X Gao… - Journal of Agricultural …, 2020 - ACS Publications
Recent evidence has revealed that probiotics could affect neurodevelopment and cognitive
function via regulating gut microbiota. However, the role of probiotics in sepsis-associated …

Supplementation with Lactobacillus helveticus NS8 alleviated behavioral, neural, endocrine, and microbiota abnormalities in an endogenous rat model of depression

H Alatan, S Liang, Y Shimodaira, X Wu, X Hu… - Frontiers in …, 2024 - frontiersin.org
Introduction Major depressive disorder is a condition involving microbiota–gut–brain axis
dysfunction. Increasing research aims to improve depression through gut microbiota …

The subcommissural organ regulates brain development via secreted peptides

T Zhang, D Ai, P Wei, Y Xu, Z Bi, F Ma, F Li… - Nature …, 2024 - nature.com
The subcommissural organ (SCO) is a gland located at the entrance of the aqueduct of
Sylvius in the brain. It exists in species as distantly related as amphioxus and humans, but its …

Microbiome mediation of animal life histories via metabolites and insulin‐like signalling

RW Warne, J Dallas - Biological Reviews, 2022 - Wiley Online Library
The regulatory pathways by which gut microbiota potentially shape host life histories remain
largely untested, however, a constellation of research suggests that gut bacteria likely have …