Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials
Traditionally, herbal supplements have shown an exceptional potential of desirability for the
prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound …
prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound …
Lipid-based nanoparticle-mediated combination therapy for breast cancer management: a comprehensive review
Breast cancer due to the unpredictable and complex etiopathology combined with the non-
availability of any effective drug treatment has become the major root of concern for …
availability of any effective drug treatment has become the major root of concern for …
Nanostructured lipid carrier-based codelivery of raloxifene and naringin: formulation, optimization, in vitro, ex vivo, in vivo assessment, and acute toxicity studies
This work aimed to develop dual drug-loaded nanostructured lipid carriers of raloxifene and
naringin (RLX/NRG NLCs) for breast cancer. RLX/NRG NLCs were prepared using …
naringin (RLX/NRG NLCs) for breast cancer. RLX/NRG NLCs were prepared using …
PEGylated liposomes as an emerging therapeutic platform for oral nanomedicine in cancer therapy: In vitro and in vivo assessment
A Singh, YR Neupane, S Shafi, B Mangla… - Journal of molecular …, 2020 - Elsevier
In the rapidly expanding field of nanomedicine, liposomes have been considered as the
most successful drug carrier having various clinically approved products. However, their …
most successful drug carrier having various clinically approved products. However, their …
Lipid-nanopotentiated combinatorial delivery of tamoxifen and sulforaphane: ex vivo, in vivo and toxicity studies
Aim: This study aims to load tamoxifen (TAM) and sulforaphane (SFN) into nanostructured
lipid carriers (NLCs) to enhance their oral delivery. Materials & methods: TAM-SFN-NLCs …
lipid carriers (NLCs) to enhance their oral delivery. Materials & methods: TAM-SFN-NLCs …
Nanostructured lipid carrier potentiated oral delivery of raloxifene for breast cancer treatment
NK Soni, LJ Sonali, A Singh, B Mangla… - …, 2020 - iopscience.iop.org
Nanotherapeutics in cancer treatment are dominating global science and research, and
have been recognized as the pioneering medical care regimen. Raloxifene (RLN) has been …
have been recognized as the pioneering medical care regimen. Raloxifene (RLN) has been …
Superparamagnetic iron-oxide nanoparticles synthesized via green chemistry for the potential treatment of breast cancer
In the emerging field of nanomedicine, nanoparticles have been widely considered as drug
carriers and are now used in various clinically approved products. Therefore, in this study …
carriers and are now used in various clinically approved products. Therefore, in this study …
Facile functionalization of Teriflunomide-loaded nanoliposomes with Chondroitin sulphate for the treatment of Rheumatoid arthritis
This research aims to coat Teriflunomide (TEF) loaded conventional nanoliposomes (CON-
TEF-LIPO) with Chondroitin sulphate (CS) to produce CS-TEF-LIPO for the effective …
TEF-LIPO) with Chondroitin sulphate (CS) to produce CS-TEF-LIPO for the effective …
NCAPD2 promotes breast cancer progression through E2F1 transcriptional regulation of CDK1
J He, R Gao, J Yang, F Li, Y Fu, J Cui, X Liu… - Cancer …, 2023 - Wiley Online Library
Breast cancer (BC) is a serious threat to women's health worldwide. Non‐SMC condensin I
complex subunit D2 (NCAPD2) is a regulatory subunit of the coagulin I complex, which is …
complex subunit D2 (NCAPD2) is a regulatory subunit of the coagulin I complex, which is …
[HTML][HTML] Systematic development and validation of RP-HPLC method for simultaneous estimation of tamoxifen and sulphoraphane with specific application for …
Abstract Tamoxifen (TAM) and Sulphoraphane (SFN) are well-known anti-estrogen drugs
used for the treatment of breast cancer. Due to their synergistic therapeutic potential, their …
used for the treatment of breast cancer. Due to their synergistic therapeutic potential, their …