Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

The WHO 2007 glioma classification system (based primarily on tumour histology) resulted
in considerable interobserver variability and substantial variation in patient survival within …

Primary brain tumors account for~ 1% of new cancer cases and~ 2% of cancer deaths in the
United States; however, they are the most commonly occurring solid tumors in children …

At the time of cancer diagnosis, body mass index (BMI) is inversely correlated with lung
cancer risk, which may reflect reverse causality and confounding due to smoking behavior …

Abstract Purpose of Review Brain and other central nervous system (CNS) tumors, while
rare, cause significant morbidity and mortality across all ages. This article summarizes the …

Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic
reactions, and their powerful effector functions activated through binding to Fc receptors …

Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Background Epidemiological studies have linked lifestyle, cardiometabolic, reproductive,
developmental, and inflammatory factors to the risk of colorectal cancer. However, which …

Background Tobacco smoking is suggested as a risk factor for colorectal cancer (CRC), but
the complex relationship and the potential pathway are not fully understood. Methods We …

Prior studies have found associations between atopic dermatitis (AD) and comorbidities
including depression, obesity, asthma, and allergic rhinitis. While observational studies often …