The global burden of lung cancer: current status and future trends

A Leiter, RR Veluswamy, JP Wisnivesky - Nature reviews Clinical …, 2023 - nature.com
Lung cancer is the leading cause of cancer-related death worldwide. However, lung cancer
incidence and mortality rates differ substantially across the world, reflecting varying patterns …

Abandoning the notion of non-small cell lung cancer

V Relli, M Trerotola, E Guerra, S Alberti - Trends in molecular medicine, 2019 - cell.com
Non-small cell lung cancers (NSCLCs) represent 85% of lung tumors. NSCLCs encompass
multiple cancer types, such as adenocarcinomas (LUADs), squamous cell cancers (LUSCs) …

[PDF][PDF] Obesity and Lung Cancer (Investigating the Relationship)

N Tzenios - EPRA International Journal of Multidisciplinary …, 2023 - researchgate.net
Obesity is a global issue, and it leads to various health comorbidities like cardiovascular
disease, diabetes type II and certain cancers. The relationship between obesity and cancer …

[HTML][HTML] Body fatness associations with cancer: evidence from recent epidemiological studies and future directions

SC Larsson, N Spyrou, CS Mantzoros - Metabolism, 2022 - Elsevier
This narrative review highlights current evidence linking greater body fatness to risk of
various cancers, with focus on evidence from recent large cohort studies and pooled …

Causal relationships between body mass index, smoking and lung cancer: univariable and multivariable Mendelian randomization

W Zhou, G Liu, RJ Hung, PC Haycock… - … journal of cancer, 2021 - Wiley Online Library
At the time of cancer diagnosis, body mass index (BMI) is inversely correlated with lung
cancer risk, which may reflect reverse causality and confounding due to smoking behavior …

Comparisons of self‐reported and measured height and weight, BMI, and obesity prevalence from national surveys: 1999‐2016

KM Flegal, CL Ogden, C Fryar, J Afful, R Klein… - …, 2019 - Wiley Online Library
Objective The aim of this study was to compare national estimates of self‐reported and
measured height and weight, BMI, and obesity prevalence among adults from US surveys …

Adolescent obesity and midlife cancer risk: a population-based cohort study of 2· 3 million adolescents in Israel

A Furer, A Afek, A Sommer, L Keinan-Boker… - The lancet Diabetes & …, 2020 - thelancet.com
Background Obesity has been established as a causal factor for several types of cancer, and
adolescent obesity is increasing worldwide. We examined associations between measured …

The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment

LZ Liu, B Wang, R Zhang, Z Wu, Y Huang… - Cell Death & …, 2023 - nature.com
Obesity/overweight and lipid metabolism disorders have become increased risk factors for
lung cancer. Fatty acid translocase CD36 promotes cellular uptake of fatty acids. Whether …

Leukotrienes in tumor-associated inflammation

W Tian, X Jiang, D Kim, T Guan, MR Nicolls… - Frontiers in …, 2020 - frontiersin.org
Leukotrienes are biologically active eicosanoid lipid mediators that originate from oxidative
metabolism of arachidonic acid. Biosynthesis of leukotrienes involves a set of soluble and …

Associations of genetic risk, BMI trajectories, and the risk of non-small cell lung cancer: a population-based cohort study

D You, D Wang, Y Wu, X Chen, F Shao, Y Wei… - BMC medicine, 2022 - Springer
Background Body mass index (BMI) has been found to be associated with a decreased risk
of non-small cell lung cancer (NSCLC); however, the effect of BMI trajectories and potential …