The different drugs and medical devices, which are commercialized or under industrial
development for glioblastoma treatment, are reviewed. Their different modes of action are …

Low-grade gliomas are slow-growing World Health Organization (WHO) grade I or II primary
brain tumors that predominantly affect young adults. WHO grade II tumors present most …

Background and purpose Target delineation in glioblastoma (GBM) varies substantially
between different institutions and several consensus statements are available. This …

Glioblastoma (GBM) is the most aggressive glial tumor of the central nervous system.
Despite intense scientific efforts, patients diagnosed with GBM and treated with the current …

The aim of this review is to explore the changing utility of radiotherapy in the treatment of
patients with glioblastoma over the past 60 years. Together with surgery, radiotherapy has …

The prognosis of patients with glioblastoma (GBM) remains poor, and the use of
hyperfractionation or dose escalation beyond 60 Gy has not conferred any survival benefit …

New evidence based regimens and novel high precision technology have reinforced the
important role of radiotherapy in the management of cancer. Current data estimate that more …

Abstract Background To integrate 3D MR spectroscopy imaging (MRSI) in the treatment
planning system (TPS) for glioblastoma dose painting to guide simultaneous integrated …

Background and purpose Resection is considered as essential for the efficacy of modern
adjuvant treatment of glioblastoma multiforme (GBM). Previous studies have indicated that …

In adults, glioma is the most commonly occurring and invasive brain tumour. For malignant
gliomas, the current advanced chemotherapy includes TMZ (temozolomide). However, a …