Natural history of venous thromboembolism

C Kearon - Circulation, 2003 - Am Heart Assoc
Most deep vein thromboses (DVTs) start in the calf, and most probably resolve
spontaneously. Thrombi that remain confined to the calf rarely cause leg symptoms or …

Deep vein thrombosis

PA Kyrle, S Eichinger - The Lancet, 2005 - thelancet.com
Deep vein thrombosis and its sequelae pulmonary embolism and post-thrombotic syndrome
are some of the most common disorders. A thrombus either arises spontaneously or is …

Recurrent venous thromboembolism after deep vein thrombosis: incidence and risk factors

PO Hansson, J Sörbo, H Eriksson - Archives of internal medicine, 2000 - jamanetwork.com
Background The recurrence rate after deep vein thrombosis (DVT) is high and the risk
factors for recurrent thromboembolic events have only been investigated on a small scale …

High plasma levels of factor VIII and the risk of recurrent venous thromboembolism

PA Kyrle, E Minar, M Hirschl… - … England Journal of …, 2000 - Mass Medical Soc
Background A high plasma level of factor VIII is a risk factor for venous thromboembolism.
We evaluated the risk of a recurrence of thrombosis after an initial episode of spontaneous …

Thrombophilia, clinical factors, and recurrent venous thrombotic events

SC Christiansen, SC Cannegieter, T Koster… - Jama, 2005 - jamanetwork.com
ContextData on the recurrence rate of venous thrombotic events and the effect of several risk
factors, including thrombophilia, remain controversial. The potential benefit of screening for …

Residual venous thrombosis as a predictive factor of recurrent venous thromboembolism

P Prandoni, AWA Lensing, MH Prins… - Annals of internal …, 2002 - acpjournals.org
Background: The optimum duration of anticoagulant therapy after an episode of deep
venous thrombosis (DVT) is controversial. Contributing to the controversy is uncertainty …

[HTML][HTML] Homocysteine, MTHFR and risk of venous thrombosis: a meta‐analysis of published epidemiological studies

M Den Heijer, S Lewington, R Clarke - Journal of Thrombosis and …, 2005 - Elsevier
Context: It has been suggested that elevated total plasma homocysteine levels are
associated with the risk of venous thrombosis. Objective: To assess the relationship of …

Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model

MA Hofmann, E Lalla, Y Lu… - The Journal of …, 2001 - Am Soc Clin Investig
Although hyperhomocysteinemia (HHcy) is a well-known risk factor for the development of
cardiovascular disease, the underlying molecular mechanisms are not fully elucidated. Here …

Prothrombin and factor V mutations in women with a history of thrombosis during pregnancy and the puerperium

A Gerhardt, RE Scharf, MW Beckmann… - … England Journal of …, 2000 - Mass Medical Soc
Background Venous thromboembolism is a leading cause of morbidity and mortality during
pregnancy and the puerperium. However, the role of mutations in the prothrombin and factor …

Hyperhomocysteinemia, atherosclerosis and thrombosis

M Cattaneo - Thrombosis and haemostasis, 1999 - thieme-connect.com
High plasma levels of homocysteine are the results of the interplay between congenital and
environmental factors. In the last two decades, a growing amount of interest has focused on …