A nanoencapsulated oral formulation of fenretinide promotes local and metastatic breast cancer dormancy in HER2/neu transgenic mice

ML De Angelis, F Francescangeli, E Aricò… - Journal of Experimental …, 2024 - Springer
Prevention and treatment of metastatic breast cancer (BC) is an unmet clinical need. The
retinoic acid derivative fenretinide (FeR) was previously evaluated in Phase I-III clinical trials …

Preclinical evaluation of fenretinide against primary and metastatic intestinal type‑gastric cancer

N Ortiz, C Díaz - Oncology Letters, 2024 - spandidos-publications.com
In recent years there has been a decline in the incidence of gastric cancer, however the high
mortality rate has remained constant. The present study evaluated the potential effects of the …

Pharmacokinetics and Tissue Distribution of Itampolin A following Intragastric and Intravenous Administration in Rats Using Ultra-High-Performance Liquid …

Q Sun, J Liang, Q Zhang, X Wang, N Zhao, F Meng - Molecules, 2024 - mdpi.com
Itampolin A, a natural brominated tyrosine alkaloid isolated from the sponge Iotrochota
purpurea, has been shown to have good inhibitory effects in lung cancer cells as a p38α …