Reproductive and Metabolic Health Following Exposure to Environmental Chemicals: Mechanistic Insights from Mammalian Models

M Bellingham, NP Evans, RG Lea… - Annual Review of …, 2024 - annualreviews.org
The decline in human reproductive and metabolic health over the past 50 years is
associated with exposure to complex mixtures of anthropogenic environmental chemicals …

Developmental programming of reproduction in the female animal

V Akbarinejad, RA Cushman - Animal Reproduction Science, 2024 - Elsevier
Successful reproduction is a cornerstone in food animal industry in order to sustain food
production for human. Therefore, various methods focusing on genetics and postnatal …

[HTML][HTML] Sexually dimorphic impact of preconceptional and gestational exposure to a real-life environmental chemical mixture (biosolids) on offspring growth dynamics …

NP Evans, M Bellingham, CS Elcombe… - Environmental …, 2023 - Elsevier
Humans are ubiquitously exposed to complex mixtures of environmental chemicals (ECs).
This study characterised changes in post-natal and peripubertal growth, and the activation of …

Developmental Programming: Sex-specific Effects of Prenatal Exposure to a Real-Life Mixture of Environmental Chemicals on Liver Function and Transcriptome in …

SV Thangaraj, M Bellingham, R Lea, N Evans… - Environmental …, 2025 - Elsevier
Humans are chronically exposed to a mixture of environmental chemicals (ECs), many with
metabolic and endocrine disrupting potential, contributing to non-communicable disease …

In-utero exposure to real-life environmental chemicals disrupts gene expression within the hypothalamo-pituitary-gonadal axis of prepubertal and adult rams

MG Hasankolaei, NP Evans, CS Elcombe, RG Lea… - Environmental …, 2025 - Elsevier
Environmental chemicals (ECs) have been associated with a broad range of disorders and
diseases. Daily exposure to various ECs in the environment, or real-life exposure, has …

Developmental programming: preconceptional and gestational exposure of sheep to biosolids on offspring ovarian dynamics

KM Halloran, Y Zhou, M Bellingham… - Biology of …, 2024 - academic.oup.com
Developmental exposure to environmental chemicals perturbs establishment and
maintenance of the ovarian reserve across the reproductive lifetime, leading to premature …