Introduction: There is a well-established relationship between sexual functioning and quality
of life. Depression can cause sexual dysfunction (SD) and its treatment can often lead to …

Introduction Sexual dysfunction (SD) is a symptom of depression in≈ 70% of patients
presenting with major depressive disorder (MDD). Antidepressant medications (AD) and …

In modern medicine, psychotropic medicines are a mainstay on many patients' medication
lists. Antidepressants are the most commonly prescribed medications in both Europe and …

P-glycoprotein (P-gp), the gene product of ABCB1, is a drug transporter at the blood–brain
barrier and could be a limiting factor for entrance of antidepressants into the brain, the target …

The P‐glycoprotein efflux pump, encoded by the ABCB1 gene, has been shown to alter
concentrations of various antidepressants in the brain. In this study, we conducted a …

Major depressive disorder is connected with high rates of functional disability and mortality.
About a third of the patients are at risk of therapy failure. Several pharmacogenetic markers …

Women experience multiple changes in social and reproductive statuses across the life
span which can affect sexual functioning. Various phases of the sexual response cycle may …

This study investigated whether Korean red ginseng (KRG) extracts could improve sexual
function in premenopausal women. Forty‐one premenopausal women participated in this …

Strategies to personalize psychopharmacological treatment promise to improve efficacy and
tolerability. We measured serotonin transporter occupancy immediately after infusion of the …

Objectives Treatment-emergent sexual dysfunction is frequently reported by individuals with
major depressive disorder (MDD) on antidepressants, which negatively impacts treatment …