Decellularized extracellular matrix-based bioinks for engineering tissue-and organ-specific microenvironments

BS Kim, S Das, J Jang, DW Cho - Chemical reviews, 2020 - ACS Publications
Biomaterials-based biofabrication methods have gained much attention in recent years.
Among them, 3D cell printing is a pioneering technology to facilitate the recapitulation of …

The extracellular matrix in ischemic and nonischemic heart failure

NG Frangogiannis - Circulation research, 2019 - Am Heart Assoc
The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …

The extracellular matrix in myocardial injury, repair, and remodeling

NG Frangogiannis - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
The cardiac extracellular matrix (ECM) not only provides mechanical support, but also
transduces essential molecular signals in health and disease. Following myocardial …

Tissue-engineered grafts from human decellularized extracellular matrices: a systematic review and future perspectives

A Porzionato, E Stocco, S Barbon, F Grandi… - International journal of …, 2018 - mdpi.com
Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

Decellularized matrices in regenerative medicine

DA Taylor, LC Sampaio, Z Ferdous, AS Gobin, LJ Taite - Acta biomaterialia, 2018 - Elsevier
Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …

[HTML][HTML] ECM and ECM-like materials—Biomaterials for applications in regenerative medicine and cancer therapy

S Hinderer, SL Layland, K Schenke-Layland - Advanced drug delivery …, 2016 - Elsevier
Regenerative strategies such as stem cell-based therapies and tissue engineering
applications are being developed with the aim to replace, remodel, regenerate or support …

Electroconductive multi-functional polypyrrole composites for biomedical applications

EN Zare, T Agarwal, A Zarepour, F Pinelli… - Applied Materials …, 2021 - Elsevier
Polypyrrole is an example of inherently electrically conductive polymer that is employed in
the biomedical arena because of its low cost, excellent electroconductive properties, and …

Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

RG Gourdie, S Dimmeler, P Kohl - Nature reviews Drug discovery, 2016 - nature.com
Our understanding of the functions of cardiac fibroblasts has moved beyond their roles in
heart structure and extracellular matrix generation and now includes their contributions to …

Bioengineering human myocardium on native extracellular matrix

JP Guyette, JM Charest, RW Mills, BJ Jank… - Circulation …, 2016 - Am Heart Assoc
Rationale: More than 25 million individuals have heart failure worldwide, with≈ 4000
patients currently awaiting heart transplantation in the United States. Donor organ shortage …

[HTML][HTML] Tissue engineering by decellularization and 3D bioprinting

E Garreta, R Oria, C Tarantino, M Pla-Roca, P Prado… - Materials Today, 2017 - Elsevier
Discarded human donor organs have been shown to provide decellularized extracellular
matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell …