Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …

The heart is a rhythmic electromechanical pump, the functioning of which depends on action
potential generation and propagation, followed by relaxation and a period of refractoriness …

Ca2+ is an essential ion in all organisms, where it plays a crucial role in processes ranging
from the formation and maintenance of the skeleton to the temporal and spatial regulation of …

Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …

To identify and localize the protein products of genes encoding distinct L-type calcium
channels in central neurons, anti-peptide antibodies specific for the class C and class D …

By the introduction of technological advancement in methods of structural analysis,
electronics, and recombinant DNA techniques, research in physiology has become …

A site-directed anti-peptide antibody, CNB-1, that recognizes the α1 subunit of rat brain class
B calcium channels (rbB) immunoprecipitated 43% of the N-type calcium channels labeled …

When a vertebrate skeletal muscle fibre is activated by a nerve impulse, an action potential
spreads from the endplate region along the whole fibre. It enters the transverse tubular …

Sydney Ringer would be overwhelmed today by the implications of his simple experiment
performed over 120 years ago showing that the heart would not beat in the absence of …

The voltage-gated Na+, Ca*+, and K+ channels are responsible for the generation of action
potentials in neurons and other excitable cells. These channels are also involved in cellular …