Glucocorticoids, genes and brain function
GR Juszczak, AM Stankiewicz - Progress in Neuro-Psychopharmacology …, 2018 - Elsevier
The identification of key genes in transcriptomic data constitutes a huge challenge. Our
review of microarray reports revealed 88 genes whose transcription is consistently regulated …
review of microarray reports revealed 88 genes whose transcription is consistently regulated …
CAS proteins in normal and pathological cell growth control
N Tikhmyanova, JL Little, EA Golemis - Cellular and molecular life …, 2010 - Springer
Proteins of the CAS (Crk-associated substrate) family (BCAR1/p130Cas, NEDD9/HEF1/Cas-
L, EFS/SIN and CASS4/HEPL) are integral players in normal and pathological cell biology …
L, EFS/SIN and CASS4/HEPL) are integral players in normal and pathological cell biology …
Discrete hippocampal projections are differentially regulated by parvalbumin and somatostatin interneurons
People with schizophrenia show hyperactivity in the ventral hippocampus (vHipp) and we
have previously demonstrated distinct behavioral roles for vHipp cell populations. Here, we …
have previously demonstrated distinct behavioral roles for vHipp cell populations. Here, we …
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
Upregulation of the scaffolding protein HEF1, also known as NEDD9 and Cas-L, has
recently been identified as a pro-metastatic stimulus in a number of different solid tumors …
recently been identified as a pro-metastatic stimulus in a number of different solid tumors …
Epigenetic regulation of BMP7 in the regenerative response to ischemia
Kidneys damaged by ischemia have the potential to regenerate through a mechanism
involving intrarenal induction of protective factors, including bone morphogenetic protein-7 …
involving intrarenal induction of protective factors, including bone morphogenetic protein-7 …
A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9
Greater understanding of metastasis is required to improve cancer treatment outcomes.
Recently, changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to …
Recently, changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to …
Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases
E Shagisultanova, AV Gaponova, R Gabbasov… - Gene, 2015 - Elsevier
Cancer progression requires a significant reprogramming of cellular signaling to support the
essential tumor-specific processes that include hyperproliferation, invasion (for solid tumors) …
essential tumor-specific processes that include hyperproliferation, invasion (for solid tumors) …
The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC
N Sima, X Cheng, F Ye, D Ma, X Xie, W Lü - PloS one, 2013 - journals.plos.org
NEDD9, a focal adhesion scaffolding protein, has been recently proposed to regulate
invasion and metastasis in some cancer types, but unknown in cervical cancer. The aim of …
invasion and metastasis in some cancer types, but unknown in cervical cancer. The aim of …
Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex
RM Tordera, AL Garcia-García, N Elizalde… - European …, 2011 - Elsevier
Major depression might originate from both environmental and genetic risk factors. The
environmental chronic mild stress (CMS) model mimics some environmental factors …
environmental chronic mild stress (CMS) model mimics some environmental factors …
Human enhancer of filamentation 1 is a mediator of hypoxia-inducible factor-1α–mediated migration in colorectal carcinoma cells
SH Kim, D Xia, SW Kim, V Holla, DG Menter… - Cancer research, 2010 - AACR
Human enhancer of filamentation 1 (HEF1; also known as NEDD9 or Cas-L) is a scaffolding
protein that is implicated in regulating diverse cellular processes, such as cellular …
protein that is implicated in regulating diverse cellular processes, such as cellular …