The multifaceted role of biological membranes prompted early the development of artificial lipid-based models with a primary view of reconstituting the natural functions in vitro so as to …
Plasma membranes are complex entities common to all living cells. The basic principle of their organization appears very simple, but they are actually of high complexity and …
Optical spectroscopies have been intensively used to determine partition coefficients by a plethora of methodologies. The present review is intended to give detailed and useful …
Derivative spectrophotometry is an analytical technique of great utility for extracting both qualitative and quantitative information from spectra composed of unresolved bands, and for …
The interaction of drugs with biological membranes is a critical factor affecting their pharmacokinetics and pharmacodynamics, so understanding how drugs interact with …
The levofloxacin hemihydrate (LH); a third generation floroquinolone antibiotic drug works against bacteria by killing bacteria or stopping their growth. But it has some side effects …
Various aspects of application of derivative spectrophotometry in chemical analysis and in investigations of equilibria and kinetics of reactions are scrutinised. The presented paper …
M Sharifian Gh - Molecular Pharmaceutics, 2021 - ACS Publications
The ability to measure the passive membrane permeation of drug-like molecules is of fundamental biological and pharmaceutical importance. Of significance, passive diffusion …
On-demand, localized release of drugs in precisely controlled, patient-specific time sequences represents an ideal scenario for pharmacological treatment of various forms of …