The transport of drugs or drug delivery systems across the cell membrane is a complex
biological process, often difficult to understand because of its dynamic nature. In this regard …

The multifaceted role of biological membranes prompted early the development of artificial
lipid-based models with a primary view of reconstituting the natural functions in vitro so as to …

Plasma membranes are complex entities common to all living cells. The basic principle of
their organization appears very simple, but they are actually of high complexity and …

Optical spectroscopies have been intensively used to determine partition coefficients by a
plethora of methodologies. The present review is intended to give detailed and useful …

Derivative spectrophotometry is an analytical technique of great utility for extracting both
qualitative and quantitative information from spectra composed of unresolved bands, and for …

The interaction of drugs with biological membranes is a critical factor affecting their
pharmacokinetics and pharmacodynamics, so understanding how drugs interact with …

The levofloxacin hemihydrate (LH); a third generation floroquinolone antibiotic drug works
against bacteria by killing bacteria or stopping their growth. But it has some side effects …

Various aspects of application of derivative spectrophotometry in chemical analysis and in
investigations of equilibria and kinetics of reactions are scrutinised. The presented paper …

The ability to measure the passive membrane permeation of drug-like molecules is of
fundamental biological and pharmaceutical importance. Of significance, passive diffusion …

On-demand, localized release of drugs in precisely controlled, patient-specific time
sequences represents an ideal scenario for pharmacological treatment of various forms of …