The inclusion of health data standards in the implementation of pharmacogenomics systems: a scoping review

D Roosan, A Hwang, AV Law, J Chok… - …, 2020 - Taylor & Francis
Background: Despite potential benefits, the practice of incorporating pharmacogenomics
(PGx) results in clinical decisions has yet to diffuse widely. In this study, we conducted a …

PriME-PGx: La Princesa University Hospital multidisciplinary initiative for the implementation of pharmacogenetics

P Zubiaur, G Mejía-Abril, M Navares-Gómez… - Journal of Clinical …, 2021 - mdpi.com
The implementation of clinical pharmacogenetics in daily practice is limited for various
reasons. Today, however, it is a discipline in full expansion. Accordingly, in the recent times …

Pharmacogenomics and personalized medicine

E Cecchin, G Stocco - Genes, 2020 - mdpi.com
Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug
selection and dosing to the patient's genetic features. In recent years, several …

Ten-year experience with pharmacogenetic testing for DPYD in a national cancer center in Italy: Lessons learned on the path to implementation

A Bignucolo, E De Mattia, R Roncato… - Frontiers in …, 2023 - frontiersin.org
Background: Awareness about the importance of implementing DPYD pharmacogenetics in
clinical practice to prevent severe side effects related to the use of fluoropyrimidines has …

[HTML][HTML] A precision medicine approach to personalized prescribing using genetic and nongenetic factors for clinical decision-making

S Jamrat, C Sukasem, L Sratthaphut… - Computers in Biology …, 2023 - Elsevier
Screening potential drug–drug interactions, drug–gene interactions, contraindications, and
other factors is crucial in clinical practice. However, implementing these screening concepts …

A genomic information management system for maintaining healthy genomic states and application of genomic big data in clinical research

JA Gim - International Journal of Molecular Sciences, 2022 - mdpi.com
Improvements in next-generation sequencing (NGS) technology and computer systems
have enabled personalized therapies based on genomic information. Recently, health …

Genomic Profiling for Predictive Treatment Strategies in Fibrotic Interstitial Lung Disease

F Perrotta, S Sanduzzi Zamparelli, V D'Agnano… - Biomedicines, 2024 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) has traditionally been considered the archetype of
progressive fibrotic interstitial lung diseases (f-ILDs), but several other f-ILDs can also …

Biomedical data science and informatics challenges to implementing pharmacogenomics with electronic health records

JM Hoffman, AJ Flynn, JE Juskewitch… - Annual Review of …, 2020 - annualreviews.org
Pharmacogenomic information must be incorporated into electronic health records (EHRs)
with clinical decision support in order to fully realize its potential to improve drug therapy …

Identification of Drugs Acting as Perpetrators in Common Drug Interactions in a Cohort of Geriatric Patients from Southern Italy and Analysis of the Gene …

M Cataldi, C Celentano, L Bencivenga, M Arcopinto… - Geriatrics, 2023 - mdpi.com
Background: Pharmacogenomic factors affect the susceptibility to drug–drug interactions
(DDI). We identified drug interaction perpetrators among the drugs prescribed to a cohort of …

Will Precision Medicine Meet Digital Health? A Systematic Review of Pharmacogenomics Clinical Decision Support Systems Used in Clinical Practice

A Farmaki, E Manolopoulos… - OMICS: A Journal of …, 2024 - liebertpub.com
Digital health, an emerging scientific domain, attracts increasing attention as artificial
intelligence and relevant software proliferate. Pharmacogenomics (PGx) is a core …