Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia

V Rausch, V Sala, F Penna, PE Porporato, A Ghigo - Oncogenesis, 2021 - nature.com
Cachexia is a severe complication of cancer that adversely affects the course of the disease,
with currently no effective treatments. It is characterized by a progressive atrophy of skeletal …

[HTML][HTML] Diagnosis and treatment of therapy-related acute myeloid leukemia

SA Strickland, N Vey - Critical reviews in oncology/hematology, 2022 - Elsevier
Therapy-related acute myeloid leukemia (t-AML), defined as AML arising from prior
cytotoxic, radiation, or immunosuppressive therapy for an unrelated disease, accounts for …

CPX-351 versus 7+ 3 cytarabine and daunorubicin chemotherapy in older adults with newly diagnosed high-risk or secondary acute myeloid leukaemia: 5-year results …

JE Lancet, GL Uy, LF Newell, TL Lin… - The Lancet …, 2021 - thelancet.com
Background Daunorubicin and cytarabine are used as standard induction chemotherapy for
patients with acute myeloid leukaemia. CPX-351 is a dual-drug liposomal encapsulation of …

Cardiovascular disease among patients with AML and CHIP-related mutations

O Calvillo-Argüelles, A Schoffel, JM Capo-Chichi… - Cardio Oncology, 2022 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP) is a novel
cardiovascular disease (CVD) risk factor in individuals without acute myeloid leukemia …

Advances in drug delivery systems for the treatment of acute myeloid leukemia

X Wu, F Wang, X Yang, Y Gong, T Niu, B Chu, Y Qu… - Small, 2024 - Wiley Online Library
Acute myeloid leukemia (AML) is a common and catastrophic hematological neoplasm with
high mortality rates. Conventional therapies, including chemotherapy, hematopoietic stem …

Targeting and Monitoring Acute Myeloid Leukaemia with Nucleophosmin-1 (NPM1) Mutation

L Chin, CYG Wong, H Gill - International Journal of Molecular Sciences, 2023 - mdpi.com
Mutations in NPM1, also known as nucleophosmin-1, B23, NO38, or numatrin, are seen in
approximately one-third of patients with acute myeloid leukaemia (AML). A plethora of …

Epigenetic changes associated with anthracycline‐induced cardiotoxicity

M Tantawy, FG Pamittan, S Singh… - Clinical and …, 2021 - Wiley Online Library
Advances in cancer treatment have significantly improved the survival of patients with
cancer, but, unfortunately, many of these treatments also have long‐term complications …

[HTML][HTML] Cardiotoxicity in Acute Myeloid Leukemia in Adults: A Scoping Study

I Konstantinidis, S Tsokkou, S Grigoriadis, L Chrysavgi… - Cancers, 2024 - mdpi.com
Simple Summary This is a scoping study aiming to extensively assess and explore the
degree of cardiotoxicity in patients with Acute Myeloid Leukemia (AML) that can be caused …

Electrocardiographic and biochemical analysis of anthracycline induced cardiotoxicity in breast cancer patients from Southern Sri Lanka

JAN Sandamali, RP Hewawasam, MACSS Fernando… - BMC cancer, 2023 - Springer
Background The clinical application of anthracycline chemotherapy is hindered due to the
cumulative dose-dependent cardiotoxicity followed by the oxidative stress initiated during …

Cardiovascular Concerns, Cancer Treatment, and Biological and Chronological Aging in Cancer: JACC Family Series

D Ioffe, SC Bhatia-Patel, S Gandhi, EA Hamad, E Dotan - Cardio Oncology, 2024 - jacc.org
Cardiovascular disease (CVD) and cancer are leading causes of death globally, particularly
among the rapidly growing population of older adults (OAs). CVD is a leading cause of …