In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

It is generally recognized that nanoparticles possess unique physicochemical properties that
are largely different from those of conventional materials, specifically the electromagnetic …

Stem cells hold great promise for the treatment of multiple human diseases and disorders.
Tracking and monitoring of stem cells in vivo after transplantation can supply important …

Mild hyperthermia is greatly beneficial to the healing of bone defects; however, how to
generat hyperthermia directly at the bone defect site remains an unsolved problem due to …

Iron oxide magnetic nanoparticles (MNPs) alone are suitable for a broad spectrum of
applications, but the low stability and heterogeneous size distribution in aqueous medium …

Nanoparticles engineered for biomedical applications are meant to be in contact with protein-
rich physiological fluids. These proteins are usually adsorbed onto the nanoparticle's …

Iron oxide nanoparticles (IONPs, sometimes called superparamagnetic iron oxide
nanoparticles or SPIONs) have already shown promising results for in vivo cell tracking …

In eukaryotic cells, mitochondrial dysfunction is associated with a variety of human diseases.
Delivery of exogenous functional mitochondria into damaged cells has been proposed as a …

Despite the high regenerative capacity of bone tissue, there are some cases where bone
repair is insufficient for a complete functional and structural recovery after damage. Current …

The use of inorganic nanoparticles as probes to label and track cells in vivo is already a
reality. While superparamagnetic nanoparticles have been the subject of clinical studies …