Novel strategies on personalized medicine for breast cancer treatment: an update
Breast cancer is the most common cancer type among women worldwide. With breast
cancer patients and survivors being reported to experience a repertoire of symptoms that are …
cancer patients and survivors being reported to experience a repertoire of symptoms that are …
Role of genetic polymorphisms in drug-metabolizing enzyme-mediated toxicity and pharmacokinetic resistance to anti-cancer agents: a review on the …
The inter-individual differences in cancer susceptibility are somehow correlated with the
genetic differences that are caused by the polymorphisms. These genetic variations in drug …
genetic differences that are caused by the polymorphisms. These genetic variations in drug …
Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor
S Balderston, JJ Taulbee, E Celaya, K Fung… - Nature Biomedical …, 2021 - nature.com
Simple and fast methods for the detection of target genes with single-nucleotide specificity
could open up genetic research and diagnostics beyond laboratory settings. We recently …
could open up genetic research and diagnostics beyond laboratory settings. We recently …
Zebrafish is a powerful tool for precision medicine approaches to neurological disorders
K Ochenkowska, A Herold, É Samarut - Frontiers in Molecular …, 2022 - frontiersin.org
Personalized medicine is currently one of the most promising tools which give hope to
patients with no suitable or no available treatment. Patient-specific approaches are …
patients with no suitable or no available treatment. Patient-specific approaches are …
Pharmacogenomics of vincristine-induced peripheral neuropathy in children with cancer: a systematic review and meta-analysis
A Uittenboogaard, CLG Neutel, JCF Ket, F Njuguna… - Cancers, 2022 - mdpi.com
Simple Summary Vincristine is a drug that is part of the treatment for many children with
cancer. Its main side-effect is vincristine-induced peripheral neuropathy (VIPN), which often …
cancer. Its main side-effect is vincristine-induced peripheral neuropathy (VIPN), which often …
Cataloging the potential SNPs (single nucleotide polymorphisms) associated with quantitative traits, viz. BMI (body mass index), IQ (intelligence quotient) and BP …
Background Single nucleotide polymorphism (SNP) variants are abundant, persistent and
widely distributed across the genome and are frequently linked to the development of …
widely distributed across the genome and are frequently linked to the development of …
Integration of pharmacogenomics and theranostics with nanotechnology as quality by design (QbD) approach for formulation development of novel dosage forms for …
To cater to medication needs in the future healthcare system, we need to shift from the
conventional system of drug delivery to modern molecular signature-based drug delivery …
conventional system of drug delivery to modern molecular signature-based drug delivery …
Pharmacogenes (PGx-genes): current understanding and future directions
Individual specific variable drug response against similar drugs raises a significant
challenge for the effective and safe treatment of many human diseases. Pharmacogenomics …
challenge for the effective and safe treatment of many human diseases. Pharmacogenomics …
[HTML][HTML] Determination of deleterious single-nucleotide polymorphisms of human LYZ C gene: an in silico study
HV Subbiah, PR Babu, U Subbiah - Journal of Genetic Engineering and …, 2022 - Elsevier
Abstract Background Single-nucleotide polymorphisms (SNPs) have a crucial function in
affecting the susceptibility of individuals to diseases and also determine how an individual …
affecting the susceptibility of individuals to diseases and also determine how an individual …
A nanopore sequencing-based pharmacogenomic panel to personalize tuberculosis drug dosing
Rationale: Standardized dosing of antitubercular drugs leads to variable plasma drug levels,
which are associated with adverse drug reactions, delayed treatment response, and relapse …
which are associated with adverse drug reactions, delayed treatment response, and relapse …