Major depression is a highly prevalent condition, affecting approximately 10% of the
population. 1 It is also a growing global problem, 2 and has been consistently associated …

Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex
human behaviors such as evaluation, affect regulation and reward-based decision-making …

Background The optimal target in the dorsolateral prefrontal cortex for treating depression
with repetitive transcranial magnetic stimulation (rTMS) remains unknown. Better efficacy …

This volume (one of two) is the first presentation of Schore's comprehensive theory in book
form, as it has developed since 1994. In 1994 Allan Schore published his groundbreaking …

A primary aim in the neuroscientific study of depression is to identify the brain areas involved
in the pathogenesis of symptoms. In this review, we describe evidence from studies …

A primary interest of the field of infant mental health is in the early conditions that place
infants at risk for less than optimal development. The fundamental problem of what …

Background: This report provides histopathological evidence to support prior neuroimaging
findings of decreased volume and altered metabolism in the frontal cortex in major …

There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin
(5HT) neurotransmitter systems in depression and anxiety disorders. The majority of …

Background Functional imaging studies of major depressive disorder demonstrate response-
specific regional changes following various modes of antidepressant treatment. Objective To …

Backgroud Major depression is a frequent psychiatric complication among patients with
traumatic brain injury (TBI). To our knowledge, however, the clinical correlates of major …