Lung cancer is one of the common malignant tumors that threaten human life with serious
incidence and high mortality. According to the histopathological characteristics, lung cancer …

Non‑small cell lung cancer (NSCLC) is a malignant tumor with a high morbidity and mortality
rate that is a threat to human health. With the development of molecular targeted research …

While significant advancements have been made in the available therapies for metastatic
non-small cell lung cancer (NSCLC), acquired resistance remains a major barrier to …

Cancer is the second-leading disease-related cause of global mortality after cardiovascular
disease. Despite significant advances in cancer therapeutic strategies, cancer remains one …

Epithelial splicing regulatory protein 1 (ESRP1) and 2 (ESRP2), epithelial cell-specific
regulators of alternative splicing, are downregulated during the epithelial–mesenchymal …

Anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) have shown dramatic
efficacy in patients with ALK-rearranged lung cancer; however, complete response in these …

Epithelial splicing regulatory protein 1 (ESRP1) is an epithelial cell-specific RNA binding
protein that controls several key cellular processes, like alternative splicing and translation …

Neural crest cells are multipotent progenitors that dynamically interpret diverse
microenvironments to migrate significant distances as a loosely associated collective and …

Gemcitabine is the first-line treatment for patients with pancreatic cancer (PC), yet most
patients develop resistance to gemcitabine. Recent studies showed that circular RNAs …

The echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase
(ALK) fusion gene occurs in approximately 5% of non-small-cell lung cancers (NSCLCs) …